Evidence map›Paper›PMID 41031565›Full record

ArticleeLife2025

Micro-scale control of oligodendrocyte morphology and myelination by the intellectual disability-linked protein acyltransferase ZDHHC9.

Hey-Kyeong Jeong, Estibaliz Gonzalez-Fernandez, Ilan Crawley, Julia M Coakley, Jinha Hwang, Dale D O Martin, Shernaz X Bamji, Jong-Il Kim, Shin H Kang, Gareth M Thomas

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hey-Kyeong Jeong *Center for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.
Estibaliz Gonzalez-Fernandez *Center for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.
Ilan CrawleyCenter for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.
Julia M CoakleyCenter for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.
Jinha HwangDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Dale D O MartinCenter for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.
Shernaz X BamjiDepartment of Cellular and Physiological Sciences, Life Sciences Institute and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0003-0102-9297
Jong-Il KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-7240-3744
Shin H KangCenter for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.ORCID https://orcid.org/0000-0002-3692-9802
Gareth M ThomasCenter for Neural Development and Repair, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.ORCID https://orcid.org/0000-0003-3183-8431

Funding

Role of Oligodendroglia in the Pathogenesis of ALSR01NS089586 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI KANG, SHIN H · 2016 to 2020
$2.1M
Roles of the X-linked Intellectual Disability gene ZDHHC9 in White Matter formationR21NS125202 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI THOMAS, GARETH · 2021 to 2021
$420k
Ellison Medical Foundation AG-NS-1101-13NINDS NIH HHS NS089586NINDS NIH HHS NS125202-01NINDS NIH HHS R01 NS089586NINDS NIH HHS R21 NS125202Shriners Hospitals for Children 87400PHI
6 · The paper itself

Abstract

Mutations in the X-linked

Indexed as

AcyltransferasesIntellectual DisabilityMyelin SheathOligodendrogliaAnimalsHumansLipoylationMiceMice, KnockoutMyelin Basic ProteinAcyltransferasesMyelin Basic ProteinZDHHC9 protein, humanintellectual disabilitymousemyelinationneuroscienceoligodendrocytepalmitoylationratS-acylation

Identifiers

PMID41031565
PMCPMC12488188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.