Evidence map›Paper›PMID 41031502›Full record

ReviewMini reviews in medicinal chemistry2025

Emerging Role of

Sanjeev Kumar Sahu, Paranjeet Kaur, Manish Vyas, Divya Chauhan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanjeev Kumar SahuSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India.ORCID 0000-0002-5472-1976
Paranjeet KaurChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India.
Manish VyasSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India.
Divya ChauhanDepartment of Pharmaceutical Chemistry, Lloyd Institute of Management and Technology, Greater Noida, Uttar Pradesh, 201306, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDendrobium belongs to one of the most important genera of the Orchidaceae family, which covers the largest category of flowering plants. More recent traditional medicinal studies have revealed that these orchid plants are used worldwide to treat a variety of illnesses, including those related to the complexion, pulmonary, gastrointestinal, reproductive, and circulatory systems, as well as cancers, pain, and inflammation. Several Dendrobium species have been the subject of phytochemistry and pharmacological research to explore their different medicinal aspects. MATERIALS AND

methodsA comprehensive search through databases (PubMed, Google Scholar, Web of Science, Traditional integrated knowledge resources, local dissertations, and books) was conducted up until November 2024 using key terms such as "Orchid plants, Type 2 diabetes, phytomedicine, natural products, phytoconstituents, phytochemistry, therapeutic potential, and plantderived antidiabetic agents."

resultsIts major phytoconstituents belong to the chemical categories of stilbenoid, glycoside, alkaloids, flavonoids, phenanthrenes, anthocyanins, carotenoids, and bibenzyl derivatives, in which the alkaloids and flavonoids play a most significant role for their biological properties. The flavone Cglycoside and flavanols are commonly found, but highly methylated and glycosylated derivatives of flavonoids are absent in orchid leaves. DISCUSSION: The phytochemical composition of Dendrobium, along with its structure-activity relationship of major classes, supports it as a potential source for novel antidiabetic agents through integrating traditional knowledge with medicinal chemistry aspects.

conclusionA specific Dendrobium orchid plant has a promising role in the effective management of diabetes. In the future, newer, more potent antidiabetic compounds may be isolated and further developed into more effective antidiabetic agents.

Indexed as

DendrobiumDiabetes Mellitus, Type 2Hypoglycemic AgentsPhytochemicalsPlant ExtractsAnimalsHumansStructure-Activity RelationshipHypoglycemic AgentsPhytochemicalsPlant ExtractsdendrobiumOrchidsphenolic acid.phytochemistrySARtherapeutic potential

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.