In one paragraphArticle in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Jorge Rojo-MenciaDepartamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0009-0004-8603-219X Lucía Alonso CarbajoDepartamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0000-0001-6613-1546 Marycarmen Arévalo-MartínezDepartamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).
Lucía Benito-SalamancaDepartamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0009-0005-6647-5636 Karel TalaveraDepartment of Cellular and Molecular Medicine, Laboratory of Ion Channel Research, KU Leuven, Belgium (L.A.C., K.T.).ORCID 0000-0002-3124-138X M Teresa Pérez-GarcíaDepartamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0000-0001-8540-8117 José Ramón López López *Departamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0000-0002-3870-421X Pilar Cidad *Departamento de Bioquímica y Biología Molecular y Fisiología, Universidad de Valladolid, and Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular (IBGM), CSIC, Valladolid, Spain (J.R.-M., L.A.C., M.A.-M., L.B.-S., M.T.P.-G., J.R.L.L., P.C.).ORCID 0000-0002-6338-7738 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundTRPM3 is a nonselective cation channel activated by heat, osmotic pressure, and neurosteroids. It is highly expressed in sensory neurons, where it integrates thermal, chemical, and inflammatory signals to modulate downstream responses, but is also present in the brain, kidney, and cardiovascular system. This distribution suggests a role in cardiovascular and renal regulation. We hypothesize that TRPM3 channels may play a role in blood pressure (BP) regulation via both vascular and renal mechanisms. Therefore, analysis of the vascular phenotype in
methodsBP was monitored noninvasively in conscious wild-type and
results
conclusionsTRPM3 channels contribute to BP regulation by modulating kidney function. Blunted tubuloglomerular feedback in
Indexed as
Blood PressureFeedback, PhysiologicalHypertensionKidneyKidney GlomerulusKidney TubulesPlasma VolumeTRPM Cation ChannelsAngiotensin IIAnimalsDisease Models, AnimalLosartanMaleMiceMice, Inbred C57BLMice, KnockoutAngiotensin IILosartanTRPM3 protein, mouseTRPM Cation Channelsangiotensin IIblood pressurehypertensionion channelskidney
Identifiers
PMID41031400
PMCPMC12626544
What OpenQuestion holds
Textmetadata
LicenceCC BY
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