Evidence map›Paper›PMID 41031358›Full record

ArticleFrontiers in nutrition2025

The inflammatory potential of diet in adults with knee osteoarthritis: sex-specific associations with quality of life, sleep, fatigue and mental health.

Lynette Law, Joshua J Heerey, Brooke L Devlin, Peter Brukner, Alysha M De Livera, James R Hebert, Sherry Price, Nathan P White, Adam G Culvenor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lynette LawLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.
Joshua J HeereyLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.
Brooke L DevlinSchool of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, QLD, Australia.
Peter BruknerLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.
Alysha M De LiveraLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.
James R HebertCancer Prevention and Control Program, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.
Sherry PriceCancer Prevention and Control Program, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.
Nathan P WhiteMelbourne Knee Centre, Melbourne, VIC, Australia.
Adam G CulvenorLa Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Knee osteoarthritis (OA) is a disabling condition-characterized by pain, stiffness, and impaired quality of life-that affects more females than males. Chronic systemic inflammation is a key feature of knee OA and can be modulated by diet. We evaluated the sex-specific relationship between the inflammatory potential of diet and health-related quality of life (HRQOL), sleep quality, energy and fatigue levels, and psychological distress in individuals with knee OA. Methods: This cross-sectional study analyzed baseline data from 144 participants (64% female) aged 45-85 years with symptomatic knee OA enrolled in the FEAST (eFEct of an Anti-inflammatory diet for knee oSTeoarthritis) randomized controlled trial, which compared an anti-inflammatory dietary program to a standard low-fat dietary program. Dietary inflammatory potential was assessed using the dietary inflammatory index (DII Results: Male and female participants had a mean ± standard deviation BMI of 30.4 ± 3.8 and 30.2 ± 7.2 kg/m Conclusion: No associations were found between dietary inflammatory potential and sleep quality, fatigue, or psychological distress. A more proinflammatory diet was linked to lower energy levels in males with symptomatic knee OA. Findings from the FEAST trial will clarify whether reducing dietary inflammation improves these outcomes over time.

Indexed as

anti-inflammatory dietchronic inflammationdietary inflammatory indexhealth-related quality of lifeosteoarthritissleep

Identifiers

PMID41031358
PMCPMC12476995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.