Evidence map›Paper›PMID 41031356›Full record

ArticleFrontiers in nutrition2025

Serum 25 (OH) D levels and risk of female-specific cancer in premenopausal women: a prospective study.

Yue Hu, Chen Zhu, Yingyi Qin, Ying Zhu, Jianzheng Zhang, Qiang Tong, Shengyun Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue Hu *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University, Shanghai, China.
Chen Zhu *College of Economics and Management, China Agricultural University, Beijing, China.
Yingyi Qin *Department of Military Health Statistics, Naval Medical University, Shanghai, China.
Ying ZhuDepartment of Pulmonary and Critical Care Medicine, 7th Medical Center of Chinese PLA General Hospital, Beijing, China.
Jianzheng ZhangDepartment of Orthopedics, The Forth Medical Center, PLA General Hospital, Beijing, China.
Qiang TongDepartment of Rheumatology and Immunology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shengyun CaiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Serum 25 (OH) D levels are associated with various diseases, including cancers, but inconsistencies exist for female-specific malignancies. This study is aimed to explore the real relationship between serum 25 (OH) D levels and incidence rates of female specific cancers in premenopausal women by a large-scale prospective cohort study. Study design: We analyzed data from 51,286 UK Biobank participants using Cox regression models to explore associations. Subgroup analyses were based on vitamin D supplementation, alcohol, smoking, BMI, diabetes, sleep, and outdoor exposure. Categorical variables were described by frequencies and compared with chi-squared tests. Results: During a median follow-up of 13.8 years, all cancer incidence was 5.1% ( Conclusion: Maintaining adequate serum 25 (OH) D levels is essential for overall health, reducing the risk of ovarian cancer, and potentially lowering susceptibility to uterine corpus cancer.

Indexed as

female-specific malignant tumorpremenopausal womenprospective cohort studyserum 25 (OH) DUK Biobankvitamin D

Identifiers

PMID41031356
PMCPMC12477915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.