ArticleJournal of inflammation research2025
Association Between High-Sensitivity C-Reactive Protein and Longitudinal Changes in Arteriosclerosis Over Time: The Kailuan Prospective Cohort Study.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association between cumulative biological risk and hypertension in older adults in Korea: a population-based cross-sectional study.Journal of Korean biological nursing science · 2026Article
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Authors and funding
9 authors.
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Abstract
Objective: To investigate the relationship between high-sensitivity C-reactive protein (hs-CRP) and the longitudinal changes in arterial Arteriosclerosis over time. Methods: Using a prospective cohort study design, 25,336 participants from the Kailuan study cohort, who had completed at least two baPWV measurements and met the inclusion criteria, included in the analysis. Participants were divided into three groups based on baseline hs-CRP levels: hs-CRP<1 mg/L, 1 mg/L≤hs-CRP≤3 mg/L, and hs-CRP >3 mg/L. The relationship between hs-CRP and the longitudinal changes in baPWV was analyzed using a linear mixed-effects model. Results: (1) The average follow-up duration was 4.62 ± 2.86 years. At the end of the follow-up, the baPWV of the three groups:hs-CRP < 1 mg/L (n=11,651), 1 mg/L ≤ hs-CRP ≤ 3 mg/L (n=9,369), and hs-CRP > 3 mg/L (n=4,316) increased over time. The average rate of increase in baPWV was 84.26 cm/s, 88.06 cm/s, and 73.92 cm/s, respectively. (2) The linear mixed-effects model analysis of factors affecting the progression of Arteriosclerosis, after adjusting for confounding factors, showed that compared to the hsCRP_1 group, the baPWV increase rate in the hsCRP_2 and hsCRP_3 groups was progressively higher. The effect Estimate were 14.4 cm/s (95% CI 6.54 to 22.34, Conclusion: There is a significant "dose-response" relationship between hs-CRP and the longitudinal progression of Arteriosclerosis, with a more pronounced effect observed in the male population.
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