Evidence map›Paper›PMID 41030993›Full record

ArticlebioRxiv : the preprint server for biology2025

Regulation of airway fumarate by host and pathogen promotes

Ying-Tsun Chen, Zihua Liu, Dario Fucich, Stefano G Giulieri, Zhe Liu, Ridhima Wadhwa, Gustavo Rios, Henning Henschel, Nupur Tyagi, Françios A B Olivier and 19 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Ying-Tsun ChenDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Zihua LiuPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Dario FucichDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Stefano G GiulieriDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.ORCID 0000-0001-5366-1943
Zhe LiuSynthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Ridhima WadhwaDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Gustavo RiosDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901, USA.
Henning HenschelDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Nupur TyagiDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901, USA.
Françios A B OlivierInfection Program and the Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Ian R MonkDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.ORCID 0000-0001-6982-8074
Shivang S ShahDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Shwetha H SridharDepartment of Genetics and Genomic Sciences, Mt. Sinai Icahn School of Medicine, New York, NY 10029, USA.
Marija DrikicDepartment of Biological Sciences, University of Calgary, Calgary, T2N 1N4, Canada.
Colleen BiancoDivision of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Gaurav K LohiaDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Ayesha Z BegDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Paul PlanetDivision of Infectious Disease, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Ian A LewisDepartment of Biological Sciences, University of Calgary, Calgary, T2N 1N4, Canada.ORCID 0000-0002-5753-499X
Robert SebraDepartment of Genetics and Genomic Sciences, Mt. Sinai Icahn School of Medicine, New York, NY 10029, USA.
Ana TravenInfection Program and the Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Abderrahman HachaniDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
Timothy P StinearDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.ORCID 0000-0003-0150-123X
Benjamin P HowdenDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia.
Jeffrey M BoydDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Sebastian A RiquelmeDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Chu WangPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Alice PrinceDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.
Tania Wong Fok LungDepartment of Pediatrics, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-9318-9572

Funding

Airway metabolites shape susceptibility to pneumoniaR01HL170129 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Alice S Prince · 2024 to 2026
$2.1M
Impact of nucleotide metabolism on bacterial clearanceR35GM146776 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sebastian Alejandro Riquelme Colet · 2022 to 2026
$2.0M
Mechanisms of cellular respiration-dependent cell lysis and its impact on biofilm formation and disassembly in Staphylococcus aureus.R01AI139100 · NIAID · RUTGERS, THE STATE UNIV OF N.J. · PI BOYD, JEFF M · 2018 to 2022
$1.9M
Understanding the immunometabolic response to Klebsiella pneumonia infectionR00HL157550 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Tania Wong Fok Lung · 2024 to 2026
$747k
Becton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413k
Understanding the immunometabolic response to Klebsiella pneumonia infectionK99HL157550 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WONG FOK LUNG, TANIA · 2022 to 2023
$244k
NCRR NIH HHS S10 RR027050NHLBI NIH HHS K99 HL157550NHLBI NIH HHS R00 HL157550NHLBI NIH HHS R01 HL170129NIAID NIH HHS R01 AI139100NIGMS NIH HHS R35 GM146776
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41030993
PMCPMC12478345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.