Evidence map›Paper›PMID 41030981›Full record

ArticlebioRxiv : the preprint server for biology2024

A sequence-specific RNA acetylation catalyst.

Supuni Thalalla Gamage, Shereen Howpay Manage, Aldema Sas-Chen, Ronit Nir, Brett W Burkhart, Isita Jhulki, Courtney N Link, Manini S Penikalapati, Jane E Jones, Lakshminarayan M Iyer and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Supuni Thalalla GamageChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.ORCID 0000-0002-1045-6306
Shereen Howpay ManageChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.ORCID 0000-0001-7280-3257
Aldema Sas-ChenThe Shmunis School of Biomedicine and Cancer Research, The George S. WIse Faculty of Life Sciences, Tel Aviv University, 6195001 Tel Aviv, Israel.ORCID 0000-0002-0347-6173
Ronit NirDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, 7630031, Israel.
Brett W BurkhartDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0002-1694-583X
Isita JhulkiChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.ORCID 0000-0003-1554-971X
Courtney N LinkChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.ORCID 0000-0001-7302-4124
Manini S PenikalapatiChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.
Jane E JonesProtein Expression Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, 21702, USA.
Lakshminarayan M IyerComputational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, USA.ORCID 0000-0002-4844-2022
L AravindComputational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, USA.ORCID 0000-0003-0771-253X
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0003-4559-3244
Schraga SchwartzDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, 7630031, Israel.ORCID 0000-0002-3671-9709
Jordan L MeierChemical Biology Laboratory, National Cancer Institute, Frederick, MD, 21702, USA.ORCID 0000-0002-0537-7101

Funding

Targeting Cancer Through Modifications and MetabolismZIABC011488 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MEIER, JORDAN L · 2013 to 2025
$21.3M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS ZIA BC011488NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

N4-acetylcytidine (ac4C) is a ubiquitous RNA modification incorporated by cytidine acetyltransferase enzymes. Here, we report the biochemical characterization of

Identifiers

PMID41030981
PMCPMC12478401

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.