Evidence map›Paper›PMID 41030926›Full record

ArticlemedRxiv : the preprint server for health sciences2025

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.

G J M S R Jayasinghe, Gu Zhu, Nirmala Pandeya, Catherine M Olsen, Nicholas G Martin, Penelope A Lind, Sarah E Medland, Scott D Gordon, Santiago D Torres, Gareth Lingham and 20 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors.

G J M S R JayasingheORCID 0000-0002-0782-0445
Gu Zhu
Nirmala Pandeya
Catherine M Olsen
Nicholas G Martin
Penelope A Lind
Sarah E Medland
Scott D Gordon
Santiago D Torres
Gareth Lingham
Samantha S Y Lee
Tamar Nijsten
Manfred Kayser
Luba M Pardo
Grant W Montgomery
Nicholas K Hayward
Jane M Palmer
David J Hunter
Jiali Han
Alex W Hewitt
Mario Falchi
D Timothy Bishop
Kevin M Brown
Veronique Bataille
David A Mackey
Mark M Iles
David C Whiteman
David L Duffy
Stuart MacGregor

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A greater understanding of the biology of nevi will provide insights into the etiology of melanoma. Our large-scale meta-analysis of 14 nevus genome-wide association study (GWAS) included 85,967 individuals of European ancestry. We identified 29 nevus-associated loci (p < 5×10

Identifiers

PMID41030926
PMCPMC12478336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.