Evidence map›Paper›PMID 41030909›Full record

ArticleRegenerative biomaterials2025

Exosome-based

Helin Xing, Yang Liu, Mi Qu, Zhengping Zhang, Yuhong Zeng, Pan Li, Qingsong Jiang, Guodong Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Helin XingDepartment of Prosthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, Beijing 100050, China.
Yang LiuDepartment of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Mi QuDepartment of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Zhengping ZhangDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Yuhong ZengDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Pan LiDepartment of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, China.
Qingsong JiangDepartment of Prosthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, Beijing 100050, China.
Guodong YangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, The Fourth Military Medical University, Xi'an 710032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic kidney disease (DKD) and osteoporosis are closely linked, yet the underlying mechanisms remain incompletely understood. DKD mouse and rat models were established via combinatorial treatment with a high-fat diet and streptozotocin, which not only induced progressive renal dysfunction, but also triggered systemic osteoporotic changes, including reduced bone mineral density, trabecular thinning and impaired bone microarchitecture. Using single-cell sequencing, we demonstrate that DKD elevates the expression of

Indexed as

diabetic kidney diseaseexosomesosteoporosisSFRP2single-cell sequencing

Identifiers

PMID41030909
PMCPMC12478701

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.