Evidence map›Paper›PMID 41030853›Full record

ArticleFrontiers in endocrinology2025

Characteristics and influencing factors of neuroendocrine dysfunction in patients with adult-onset craniopharyngioma.

Ying Guo, Songbai Gui, Pinan Liu, Yazhuo Zhang, Liyong Zhong, Jian Xu

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying GuoDepartment of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Songbai GuiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Pinan LiuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yazhuo ZhangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Liyong ZhongDepartment of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jian XuDepartment of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of the study was to compare neuroendocrine dysfunction patterns in adult-onset adamantinomatous craniopharyngiomas (ACPs) and papillary craniopharyngiomas (PCPs) before and after surgery, and identify factors that influence neuroendocrine outcomes in these two histopathological types. Methods: A retrospective analysis was conducted on 390 patients with adult-onset craniopharyngioma (CP) patients, including 272 patients with ACP and 118 patients with PCP. The pre- and post-operative neuroendocrine parameters were compared, and the factors that contributed to poor endocrine outcomes were identified. Results: Suprasellar tumor extension (83.1% Conclusions: Surgical intervention may exacerbate pituitary dysfunction in adult patients with ACP and PCP, although different factors influence the adverse endocrine outcomes for these two pathological types.

Indexed as

CraniopharyngiomaNeurosecretory SystemsPituitary NeoplasmsAdolescentAdultAgedAge of OnsetFemaleHumansMaleMiddle AgedRetrospective StudiesYoung Adultadamantinomatous craniopharyngiomaadenohypophyseal dysfunctionclinical prognosisdiabetes insipiduspapillary craniopharyngioma

Identifiers

PMID41030853
PMCPMC12477007

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.