Evidence map›Paper›PMID 41030827›Full record

ArticleOphthalmology science2026

Association between Choroidal Vascular Hyperpermeability and Vortex Vein Anastomoses in Central Serous Chorioretinopathy.

Yasunori Miyara, Nobuhiro Terao, Naoya Imanaga, Hideki Koizumi

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In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yasunori MiyaraDepartment of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Nobuhiro TeraoDepartment of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Naoya ImanagaDepartment of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Hideki KoizumiDepartment of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the association between choroidal vascular hyperpermeability (CVH) and vortex vein anastomoses in the macula of patients with central serous chorioretinopathy (CSC). Design: A retrospective comparative study. Subjects: A total of 118 eyes of 106 patients with CSC. Methods: All patients underwent choroidal en face imaging using widefield swept-source OCT. The eyes were classified into watershed zone (WZ) and non-WZ groups. The horizontal WZ through the macula was identified in the WZ group, whereas it was ill-defined in the non-WZ group, because of marked anastomoses between the superior and inferior vortex veins. The number and distribution of CVH areas, as detected on indocyanine green angiography, were evaluated and compared between the 2 groups. Main Outcome Measures: Association between CVH and vortex vein anastomoses in CSC. Results: Overall, 118 eyes were classified into the WZ (n = 81) and non-WZ (n = 37) groups. The mean number of CVH areas per eye was significantly higher in the non-WZ group than in the WZ group (4.95 vs. 2.43; Conclusions: Central serous chorioretinopathy eyes with an ill-defined WZ due to marked vortex vein anastomoses had more multifocal and extensive CVH areas than those with an identified WZ. The presence of vortex vein anastomoses may affect the number and distribution of CVH areas in eyes with CSC. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

Central serous chorioretinopathyChoroidal vascular hyperpermeabilityVortex vein anastomosesWatershed zoneWidefield OCT

Identifiers

PMID41030827
PMCPMC12478076

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.