ReviewJournal of pain research2025
Acupuncture in Knee Osteoarthritis: A Narrative Review of Clinical Efficacy and Neuroimmune-Endocrine Mechanisms.
Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Shuci method of electroacupuncture improves self-perception and quality of life in patients with knee osteoarthritis: a multicenter randomized controlled trial.Frontiers in medicine · 2026Trial
- Effectiveness and multidimensional mechanisms of close-to-bone needling in knee osteoarthritis: a randomized controlled trial.American journal of translational research · 2026Article
- Pain Modulation, Inflammation-Regulatory Mechanisms, and Translational Boundaries of Evidence for Acupuncture-Related Therapies in Knee Osteoarthritis: A Structured Narrative Review.Journal of pain research · 2026Review
- Acupoint Selection Patterns and Potential Mechanisms of Acupuncture in Knee Osteoarthritis: A Combined Data Mining and Network Pharmacology Study.Journal of pain research · 2026Article
- Evaluating the Effect of Electroacupuncture in Knee Osteoarthritis: Protocol for a Multicenter Randomized Controlled Trial.Journal of pain research · 2026Article
- Different Acupuncture Therapies for Postoperative Residual Pain Following PKP/PVP for Osteoporotic Vertebral Compression Fractures: A Protocol for a Systematic Review and Bayesian Network Meta-Analysis.Journal of pain research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Knee osteoarthritis (KOA) is a leading cause of global pain and disability and warrants complementary therapy. This review provides evidence of the clinical efficacy of acupuncture and the multisystem regulatory mechanisms of KOA. Methods: We analyzed clinical trials and mechanistic studies of acupuncture in the treatment of KOA. Results: Acupuncture-particularly electroacupuncture (EA) significantly reduced pain (VAS/WOMAC) compared with sham acupuncture and conventional care ( Conclusion: Acupuncture is an effective complementary therapy for KOA. Future research should prioritize long-term efficacy, personalized protocols, technology integration, and multidisciplinary strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.