ReviewCureus2025
Oral Biofilm and Gender-Specific Health Considerations.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral biofilm plays a central role in the development of periodontal and systemic diseases, with growing evidence highlighting significant gender-specific differences. Hormonal fluctuations in women, during puberty, menstruation, pregnancy, menopause, and with oral contraceptive use, may alter the composition and behavior of oral biofilm, increasing susceptibility to gingival inflammation and periodontal disease. Conditions such as polycystic ovary syndrome (PCOS), osteoporosis, and pregnancy-associated gingivitis further demonstrate the influence of endocrine factors on oral health. In men, higher rates of severe periodontitis are observed, potentially linked to testosterone-related immune responses and behavioral factors with associations to lower sperm counts, increased incidence of prostate cancer, and erectile dysfunction. These distinctions underscore the importance of considering sex-specific biology in both the prevention and management of oral and systemic diseases influenced by biofilm. This study reviews the connections between gender-specific health and oral biofilm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.