Evidence map›Paper›PMID 41030732›Full record

ArticleCureus2025

Cancer-Associated Venous Thromboembolic Disease: Anatomoclinical Aspects and Risk Factors.

Imen Ketata, Aloulou S Samir, Abir Bouassida, Faten Dhouib, Manel Bahri, Hadil Chaari, Hamdani Moez, Rahma Kallel, Hayfa Rajhi

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Imen KetataDepartment of Medical Oncology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Aloulou S SamirDepartment of Medical Oncology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Abir BouassidaDepartment of Cardiology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Faten DhouibDepartment of Cardiology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Manel BahriDepartment of Radiotherapy, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Hadil ChaariDepartment of Medical Oncology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Hamdani MoezAnatomopathology Laboratory, Faculty of Medicine, University of Sfax, Sadok Mkaddem Hospital, Djerba, TUN.
Rahma KallelDepartment of Cardiology, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabes, TUN.
Hayfa RajhiMedical Analysis Laboratory, Faculty of Medicine, University of Sfax, Gabes University Hospital, Gabès, TUN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cancer represents an independent risk factor for venous thromboembolic disease (VTE). The main objective of this study is to analyze the cancer profile as well as the related VTE risk factors. Materials and methods A retrospective, descriptive, and analytical study was conducted in the Gabes University Hospital from January 2017 to May 2021. The data study collection focused on patients hospitalized with VTE-associated cancer. Input data and statistical analysis were performed using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States). Results The study involved 135 patients. The average age of the patients was 59.21 years, ranging from 17 to 94 years, and the sex ratio of 1.81. Lung, pancreatic, and bladder cancers significantly increased the risk of VTE by 1.48 (95% CI [1.19-1.85]), 2.60 (95% CI [1.31-5.3]), and 2.61 (95% CI [1.26-5.4]), respectively. Among the patients with metastatic cancer, the risk of developing VTE was 1.55 times higher than patients without metastatic cancer (95% CI [1.1-2.1]). Small cell, squamous cell, and urothelial carcinoma significantly increased (p<0.001) the risk of VTE occurrence by 2.79 (95% CI [1.69-4.6]), 2.41 (95% CI [1.38-4.13]), and 3.03 (95% CI [1.33-6.8]), respectively. Conclusion Among the patients with metastatic cancer, the risk of developing VTE was higher than patients without metastatic cancer. In addition, small cell, squamous cell, and urothelial carcinoma significantly increased the risk of VTE. Problems and knowledge of the VTE risk factors among cancer patients allow for cancer management improvement as well as avoiding further thromboembolic complications.

Indexed as

canceroncologyrisk factorthrombosisvenous thromboembolic disease

Identifiers

PMID41030732
PMCPMC12477556

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.