ArticleCureus2025
Prevalence and Predictors of Post-coital Hypoglycemia in Diabetes Mellitus.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Post-coital hypoglycemia is a significant yet often overlooked complication in diabetes management. This cross-sectional study aimed to assess the prevalence and associated factors of post-coital hypoglycemia among patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in Al-Ahsa, Saudi Arabia. A total of 821 participants were interviewed via telephone using a structured questionnaire. The study revealed that 17.9% of participants experienced hypoglycemic events during or after sexual activity. Insulin use was strongly associated with post-coital hypoglycemia, with 28.3% of insulin users reporting such events compared to only 3.0% of non-insulin users (p<0.001). T1DM patients were significantly more likely to experience post-coital hypoglycemia than T2DM patients (92.5% vs 7.5%, p<0.001). Younger age groups, higher educational levels, and married status were also associated with increased incidence. Common symptoms reported included sweating (47.6%), palpitations (42.0%), and dizziness (37.3%). The use of certain oral diabetic medications, including metformin, sitagliptin, and gliclazide-sulfonylurea, was also associated with higher rates of post-coital hypoglycemia. These findings highlight the need for increased awareness and targeted interventions to address post-coital hypoglycemia in diabetes management. Healthcare providers should incorporate discussions about sexual health and hypoglycemia risk into routine diabetes care, particularly for high-risk groups such as insulin users and T1DM patients. Future research should focus on developing effective strategies to prevent and manage post-coital hypoglycemia, thereby improving the quality of life for individuals with diabetes.
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