Evidence map›Paper›PMID 41030695›Full record

ArticleFrontiers in dental medicine2025

Mineralization, anti-demineralization, and antibacterial effects of novel Bioactive Universal Bond with calcium salt monomers on dental caries.

Bayarchimeg Altankhishig, Yasuhiro Matsuda, Yaxin Rao, Takashi Saito

Abstract read
In one paragraph

Article in Frontiers in dental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bayarchimeg Altankhishig *Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Yasuhiro Matsuda *Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Yaxin RaoDivision of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.
Takashi SaitoDivision of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Tobetsu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the mineralization, anti-demineralization, and antibacterial properties of a novel bioactive universal adhesive containing the calcium salt of 4-methacryloxyethyl trimellitate acid (CMET). Four adhesives were evaluated: Bioactive Universal Bond with CMET (BA), Clearfil Universal Bond Quick (CU), Prime & Bond Universal (PB), and Scotchbond Universal Plus Adhesive (SUB). To assess mineralization properties, BA specimens were immersed in simulated body fluid (SBF) at 37°C, in line with ISO 23317, and the induced crystals were analyzed using scanning electron microscopy and energy dispersive x-ray spectroscopy. Anti-demineralization was evaluated by applying each adhesive to polished bovine dentin, followed by a one-week pH cycling protocol. Transverse microradiography (TMR) was used to quantify the integrated mineral loss. The antibacterial activity was assessed using eluates prepared by immersing the cured specimens in distilled water for seven days, followed by serial dilutions (10%, 5%, 1%, and 0.5%). These eluates were incubated with

Indexed as

antibacterial effectanti-demineralizationBioactive Universal BondCMETmineralizationmultifunctional material

Identifiers

PMID41030695
PMCPMC12477213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.