Evidence map›Paper›PMID 41030665›Full record

ArticleHealth science reports2025

Impact of Change, Fluctuation, or Variability in Weight on the Risk of Nonalcoholic Fatty Liver Disease in General Population: A Systematic Review and Meta-Analysis.

Dorsa Alijanzadeh, Masoud Noroozi, Negin Rostami, Narges Norouzkhani, Mahdie ShojaeiBaghini, Saeed Zivari Lashkajani, Ali Mirzaei, Maryam Dianati, Maryam Salimi, Hamidreza Sadeghsalehi and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dorsa AlijanzadehSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Masoud NorooziDepartment of Biomedical Engineering, Faculty of Engineering University of Isfahan Isfahan Iran.
Negin RostamiDepartment of Medical Islamic Azad Univeristy of Mashhad Mashhad Iran.
Narges NorouzkhaniDepartment of Medical Informatics, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-9734-9126
Mahdie ShojaeiBaghiniMedical Informatics Research Center, Institute for Futures Studies in Health Kerman University of Medical Sciences Kerman Iran.ORCID https://orcid.org/0000-0002-9857-7347
Saeed Zivari LashkajaniKashan University of Medical Sciences Kashan Iran.
Ali MirzaeiMashhad University of Medical Sciences Mashhad Iran.
Maryam DianatiRafsanjan University of Medical Sciences Rafsanjan Iran.
Maryam SalimiDepartment of Pharmacy Zanjan University of Medical Sciences Zanjan Iran.
Hamidreza SadeghsalehiDepartment of Artificial Intelligence in Medical Sciences Iran University Of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0001-9783-7795
Faezeh JadidianSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Sajjad Ghane EzabadiMultiple Sclerosis Research Center, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran.
Mohammad Sadegh FallahiSchool of Medicine Tehran University of Medical Sciences Tehran Iran.
Mobina FathiSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-4811-3982
Alaleh AlizadehFaculty of Medicine, Mashhad Branch Islamic Azad University Mashhad Iran.
Mahsa Asadi AnarSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-5772-2472
Niloofar DeraviSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-6965-6927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Numerous studies on the impact of weight changes on nonalcoholic fatty liver disease are being conducted; therefore, this systematic review aims to critically discuss the impact of change, fluctuation, or variability in weight on the risk of nonalcoholic fatty liver disease in the general population. Methods: Data from three databases, PubMed/Medline, Google Scholar, and Scopus, which were available until June 2024, were used to compile the materials for our research. Only English-language publications were submitted for this study, and they were evaluated based on their titles, abstracts, and complete texts and. Result: Eight studies (three cross-sectional articles and five cohort articles) involving 147,601 participants from Japan, China, Korea, and the United States were included. The results of this study showed that weight loss had significantly increased odds of developing NAFLD independently and per 1 kg compared to the stable weight control group. (OR = 1.16, 95% CI: 1.118-1.208, Conclusion: Nonalcoholic fatty liver disease is increasing in industrialized nations and has a significant financial impact on people's health and healthcare systems. It can be controlled by emphasis on reducing weight change and maintaining a healthy weight.

Indexed as

body weight changesNAFLDnonalcoholic fatty liver diseaseobesity

Identifiers

PMID41030665
PMCPMC12477495

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.