Evidence map›Paper›PMID 41030662›Full record

ArticleHealth science reports2025

Trigger Factors of Primary Cerebral Hemorrhage Onset: A Case-Crossover Study.

Yun-Tao Pu, Yan-Yue Wang, Ya-Yun Xiang, Miao Zhao

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yun-Tao PuDepartment of Neurology The Affiliated Rehabilitation Hospital of Chongqing Medical University Chongqing China.ORCID https://orcid.org/0000-0002-8974-7527
Yan-Yue WangDepartment of Neurology University-Town Hospital of Chongqing Medical University Chongqing China.ORCID https://orcid.org/0000-0001-8765-4661
Ya-Yun XiangDepartment of Neurology University-Town Hospital of Chongqing Medical University Chongqing China.
Miao ZhaoDepartment of Neurology The Affiliated Rehabilitation Hospital of Chongqing Medical University Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Compared to traditional chronic risk factors, our understanding of trigger factors for cerebral hemorrhage (ICH) remains relatively primitive. This study aims to identify common trigger factors associated with ICH onset and investigate their diurnal variations in exposure patterns. Methods: The study population comprised patients with first-ever primary ICH in Chongqing, Southwest China from January 1, 2024 to December 31, 2024. This is a case-crossover study, and we compared each patient's exposure during case periods with their own control periods. Through comparative analysis between trigger periods and stable periods, we identified potential trigger factors and further examined diurnal exposure differences between daytime and nighttime. Results: The study included 1088 ICH patients (mean age 59.6 ± 16.1 years; 632 males [58.1%]). Significant triggers included Valsalva maneuvers (OR 3.05, 95% CI: 2.43-3.83, Conclusion: We identified several triggering factors associated with ICH onset, some of which exhibited distinct diurnal variations in exposure patterns. These findings provide novel insights into the pathophysiology of cerebrovascular rupture and offer evidence-based references for targeted ICH prevention strategies.

Indexed as

cerebral hemorrhageriskstrenuous exercisetrigger factorValsalva maneuvers

Identifiers

PMID41030662
PMCPMC12477487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.