ReviewWorld journal of oncology2025
IgM Myeloma: A Comprehensive Overview and Practical Approach to Chemotherapeutic Management.
Review in World journal of oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgM myeloma is a rare subtype of multiple myeloma (MM) comprising 0.5% of all of its cases. It is characterized by the unregulated proliferation of IgM-secreting plasma cells in the bone marrow. The underlying pathogenesis involves dysregulation of isotype switch recombination, leading to various translocations involving chromosomes such as 11q13 and 4p16. Patients usually present with symptoms of hyperviscosity syndrome, bone marrow infiltration, and organomegaly. Diagnostic workup includes clinical evaluation, laboratory tests (electrophoresis, bone marrow biopsy, cytogenetics, immunohistochemistry), and imaging. Treatment options for IgM myeloma include proteasome inhibitors, immunomodulatory drugs, monoclonal antibodies, and autologous stem cell transplantation. However, no clear management guidelines are established for this rare subtype of MM. This article provides an up-to-date detailed overview of the pathogenesis, clinical features, and diagnostics of IgM myeloma.
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Registered trials
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