Evidence map›Paper›PMID 41030612›Full record

ReviewBJR artificial intelligence2025

General artificial intelligence for the diagnosis and treatment of cancer: the rise of foundation models.

Ali A Tarhini, Palak Dave, Issam El Naqa

Abstract readReview
In one paragraph

Review in BJR artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali A TarhiniDepartment of Machine Learning, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States.ORCID https://orcid.org/0009-0000-9845-4972
Palak DaveDepartment of Machine Learning, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States.ORCID https://orcid.org/0000-0002-7107-3085
Issam El NaqaDepartment of Machine Learning, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States.ORCID https://orcid.org/0000-0001-6023-1132

Funding

Optimal Decision Making in Radiotherapy Using Panomics AnalyticsR01CA233487 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2019 to 2023
$2.4M
NCI NIH HHS R01 CA233487
6 · The paper itself

Abstract

Artificial intelligence (AI) and its computer algorithms, including those of machine learning and deep learning, have been transforming the oncology field. Generative AI (Gen AI) and general AI technologies, which can be adapted to various tasks based on diverse inputs, are being increasingly utilized in healthcare applications. Foundation models, driven by Gen AI and general AI technologies, have enthralled the medical world, representing the next generation of large-scale AI tools in medicine that are trained on massive amounts of data and will make a major impact due to their versatility, high performance, personalization enhancement, and assistance of healthcare workers. That said, it is undeniable that there are multiple obstacles that these algorithms must overcome to be successfully utilized in the field. In this review, we first present a brief background and a history of the recent rise of Gen AI and foundation models. Next, we explore their applications in the diagnosis and treatment of cancer, specifically in radiology, pathology, precision medicine, personalization of care, and surgical oncology. Then, we discuss some of the limitations that could hinder general and Gen AI's clinical translation.

Indexed as

AI agentsartificial intelligencefoundation modelsgeneral AIgenerative AImachine learningoncology

Identifiers

PMID41030612
PMCPMC12478997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.