ArticleFrontiers in pediatrics2025
Pathogen distribution and liver injury severity in children with community-acquired pneumonia complicated by liver injury in Suzhou, China.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Factors associated with in-hospital mortality and treatment withdrawal in mechanically ventilated children with severe pneumonia: a retrospective cohort study.Translational pediatrics · 2026Article
- Development of a nomogram to predict acute liver injury in children withFrontiers in pediatrics · 2026Article
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Authors and funding
3 authors.
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Abstract
Background: Liver injury is a extrapulmonary complication of community-acquired pneumonia (CAP). However, limited data exist on the pathogen distribution and severity of liver injury in children with CAP-associated liver injury. This study aimed to investigate the characteristics of pathogen distribution and the severity of liver injury in children with CAP complicated by liver injury in the Suzhou area. Methods: A retrospective study was conducted on children with CAP hospitalized at the Children's Hospital of Soochow University between January 2018 and December 2022. The study included children aged over 28 days to under 18 years, categorized into the following age groups: >28 days to 1 year, >1-3 years, >3-5 years, and >5 years. Laboratory examination results, pathogens, and characteristics of liver injury were analyzed. Results: Among the 1525 children with CAP complicated by liver injury, the male-to-female ratio was 1.4:1. Mild elevation of transaminases were observed in 1,403 cases. In the same age group, there were differences in the proportion of cases with varying degrees of liver injury ( Conclusions: In the Suzhou area, children with CAP aged >28 days to 1 year were the most susceptible to liver injury, with mild elevation of transaminases being the most common presentation. Special attention was required for children with CAP complicated by
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