Evidence map›Paper›PMID 41030511›Full record

ArticleToxicology research2025

Integrative In vitro and In Silico analysis of marine Actinobacterium,

Ambily Balakrishnan, Kottayath G Nevin, Arunkumar Gangadharan, V P Limnamol

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ambily BalakrishnanDepartment of Marine Biosciences, Faculty of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad, Kochi, Ernakulam District, Kerala 682506, India.
Kottayath G NevinDepartment of Marine Biosciences, Faculty of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad, Kochi, Ernakulam District, Kerala 682506, India.ORCID https://orcid.org/0000-0002-0844-9342
Arunkumar GangadharanDepartment of Molecular Biology, Dr. Janaki Ammal Campus, Kannur University, Kannur District, Kerala 670661, India.
V P LimnamolDepartment of Marine Biosciences, Faculty of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad, Kochi, Ernakulam District, Kerala 682506, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quorum-sensing (QS), a bacterial communication mechanism regulating virulence, biofilm formation, and environmental adaptation, represents a promising target for antivirulence therapies. Unlike conventional antibiotics, QS inhibition disrupts bacterial coordination without promoting antimicrobial resistance. Marine actinobacteria, well adapted to extreme habitats, are a rich source of bioactive quorum-sensing inhibitors (QSI). This study evaluates the QSI activity of ethyl acetate (EA) extract from a marine actinobacterium,

Indexed as

antimicrobial resistancebioactive compoundsbiofilm formationChromobacterium violaceummarine actinobacteriaquorum-sensingStreptomyces rubrogriseus

Identifiers

PMID41030511
PMCPMC12477593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.