Evidence map›Paper›PMID 41030489›Full record

ArticleJournal of medical cases2025

Quantitative Train-of-Four Monitoring Using the TetraGraph™ to Evaluate Rocuronium Requirements During Renal Transplantation in a Pediatric Patient.

Wajahat Nazir, Edison E Villalobos, Stephania Paredes Padilla, Gregory Maves, Joseph D Tobias

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wajahat NazirDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Edison E VillalobosDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Stephania Paredes PadillaDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Gregory MavesDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Joseph D TobiasDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacokinetics of neuromuscular blocking agents (NMBAs) may be altered in patients with renal insufficiency or failure, including alterations in the volume of distribution or elimination of the primary drug and its metabolites. In this patient population, monitoring of the end-organ effects of NMBAs may be useful to guide initial and subsequent dosing, as well as reversal of neuromuscular blockade. Train-of-four (TOF) monitoring remains the most commonly used technique to monitor the end-organ effect of NMBAs and the neuromuscular junction. Here we present the use of an electromyography (EMG)-based TOF monitor in a 9-year-old boy with end-stage renal disease during intraoperative anesthetic care for renal transplantation. The perioperative management of such patients, including dosing of NMBAs and use of neuromuscular blockade monitoring, is discussed.

Indexed as

Neuromuscular blockadeNeuromuscular blocking agentsRenal failureRenal transplantationRocuroniumTrain-of-four monitor

Identifiers

PMID41030489
PMCPMC12479079

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.