Outcomes of transsphenoidal surgery in 34 small dogs with pituitary-dependent hypercortisolism.

Sachiyo Tanaka, Shuji Suzuki, Takahiro Teshima, Hirokazu Ishino, Asaka Kawana, Takahiro Taoda, Yasushi Hara

Abstract read

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sachiyo TanakaLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Shuji SuzukiLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Takahiro TeshimaLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Hirokazu IshinoLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Asaka KawanaLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Takahiro TaodaLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Yasushi HaraLaboratory of Veterinary Surgery (Tanaka, Suzuki, Hara) and Laboratory of Veterinary Internal Medicine (Teshima), Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino-shi, Tokyo 180-8602, Japan; Laboratory of Small Animal Surgery 1, Faculty of Veterinary Science, Kitasato University, 35-1 Higashi 23-bancho, Towada-shi, Aomori 034-0021, Japan (Ishino); Tokyo University of Agriculture and Technology Animal Medical Center, 3-5-8 Saiwai, Fuchu, Tokyo 183-0054, Japan (Kawana); Kasai Rinkai Veterinary Hospital, 6-2-3 Nakakasai, Edogawa-ku, Tokyo 134-0083, Japan (Taoda).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to evaluate the clinical outcomes of transsphenoidal surgery (TSS) in dogs weighing < 15 kg with pituitary-dependent hypercortisolism (PDH). Animals: The study included 34 dogs, each weighing < 15 kg, diagnosed with PDH, and undergoing TSS at our facility between 1999 and 2021. Procedure: Postoperative assessments included fatal complications within 4 wk, the extent of mass resection, the duration of central diabetes insipidus, long-term survival, and duration of remission. Results: Five dogs died within 4 wk after TSS. Complete resections were completed in 28 dogs, whereas 6 dogs underwent partial resection. Factors associated with partial resection included a higher pituitary-to-brain ratio (odds ratio: 112 705.8; Conclusion and clinical relevance: Transsphenoidal surgery is an effective treatment for PDH in dogs weighing < 15 kg, particularly when the pituitary gland is small.

Indexed as

DogsPituitary ACTH HypersecretionPituitary GlandSphenoid SinusAnimalsBody WeightDiabetes Insipidus, NeurogenicPostoperative ComplicationsTransanal Endoscopic SurgeryTreatment Outcome

Identifiers

PMID41030423

PMCPMC12477731

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.