Evidence map›Paper›PMID 41030279›Full record

ReviewBioengineering & translational medicine2025

Mitochondrial and photosynthetic therapy: A crucial strategy for remodeling cellular metabolic function.

Muhammad Samee Mubarik, Zizhen Zhao, Mehdi Khoshnamvand, De-Sheng Pei, Ailing Fu

Abstract readReview
In one paragraph

Review in Bioengineering & translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Samee MubarikCollege of Pharmaceutical Science Southwest University |Chongqing China.ORCID https://orcid.org/0000-0002-6277-5763
Zizhen ZhaoCollege of Pharmaceutical Science Southwest University |Chongqing China.
Mehdi KhoshnamvandCaspian Sea Ecology Research Center (CSERC), Iranian Fisheries Science Research Institute (IFSRI) Agricultural Research, Education and Extension Organization (AREEO) Sari Iran.
De-Sheng PeiSchool of Public Health Chongqing Medical University Chongqing China.ORCID https://orcid.org/0000-0001-6408-9575
Ailing FuCollege of Pharmaceutical Science Southwest University |Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extranuclear organelle transplantation, an emerging field in cell biology and bioengineering, presents innovative therapeutic possibilities by transferring organelles such as mitochondria between cells or across species. In living organisms, mitochondria and chloroplasts are closely related to converting substances and energy within cells. Transplantation therapy of mitochondria seeks to rebuild cell metabolic function in diseased or damaged cells and has broad application potential in treating metabolic diseases. The therapies provide a distinctive technology for cellular restoration by targeting energy generation at the organelle level, which will offer new energy resources for animal cells. At present, mitochondrial transplantation therapy has been applied as a novel approach to rescue patients in clinical settings, and chloroplast-based transplantation endows animal cells to utilize light energy (photosynthetic animal cells). In this review, we discuss the exciting development and application prospects of mitochondrial and photosynthetic therapy in biomedicine. The technology of extranuclear transplantation would exert innovative and profound impacts on biological therapy.

Indexed as

cellular new energy resourceschloroplastsclinical applicationsmitochondria

Identifiers

PMID41030279
PMCPMC12478445

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.