Evidence map›Paper›PMID 41030238›Full record

ArticleInfection and drug resistance2025

Establishment of a Machine Learning-Based Predictive Model for

Haoran Li, Yan Yu, Xi Chen, Qingqing Sun, Xiumin Li, Qiujing Shang, Minghua Ying, Xiulin Liu, Jing Meng, Lele Bian and 2 more

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Haoran LiSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.ORCID 0009-0000-4288-499X
Yan YuSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Xi ChenDepartment of Ultrasound, Tianjin Third Central Hospital, Tianjin, 300170, People's Republic of China.ORCID 0009-0004-9523-0817
Qingqing SunSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Xiumin LiSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Qiujing ShangSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Minghua YingSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Xiulin LiuSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Jing MengOutpatient Department Comprehensive Treatment Room, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Lele BianDepartment of Radiology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Shanshan WuSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.
Yuejuan GaoSenior Department of Oncology, Chinese PLA General Hospital, Beijing, 100039, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the clinical and ultrasonographic characteristics of pyogenic liver abscess (PLA) caused by Materials and Methods: In this retrospective study, patients clinically diagnosed with PLA and confirmed by ultrasound-guided puncture at the Fifth Medical Center of PLA General Hospital between April 2013 and December 2020 were enrolled. Based on the causative pathogens, patients were categorized into K-PLA and non-K-PLA groups. Baseline data, including ultrasonographic features, clinical characteristics, and laboratory findings, were collected. The Boruta algorithm was employed for feature selection, and four machine learning models-Deep Learning-Fully Connected Neural Network (deeplearning), Distributed Random Forest (drf), Gradient Boosting Machine (gbm), and Generalized Linear Model (glm)-were developed to diagnose K-PLA. The models were validated using 5-fold cross-validation. Results: A total of 201 patients with bacterial liver abscess were included (median age: 57 years; range: 49-66; 136 males), comprising 134 K-PLA cases and 67 non-K-PLA cases. The Boruta algorithm identified seven significant predictive variables: history of diabetes, history of hepatocellular carcinoma, history of biliary tract disease, history of infectious diseases, duration of fever, body temperature, and alanine aminotransferase (ALT) levels. Using these variables, the four machine learning models were constructed. In the training set, the area under the receiver operating characteristic curve (AUC) for predicting K-PLA was 0.716 (deeplearning), 0.999 (drf), 0.922 (gbm), and 0.718 (glm). In the validation set, the corresponding AUC values were 0.799, 0.763, 0.848, and 0.805, respectively. Conclusion: This study successfully established four machine learning models for predicting the risk of K-PLA, with the gbm-based model demonstrating the highest diagnostic performance. These models may facilitate early clinical diagnosis and treatment of K-PLA, thereby reducing antibiotic misuse.

Indexed as

Klebsiella pneumoniaeliver abscessmachine learningmisuse of antibioticspredictive model

Identifiers

PMID41030238
PMCPMC12477283

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.