Evidence map›Paper›PMID 41030122›Full record

ArticleMicrobial biotechnology2025

Mapping and Cataloguing Microbial and Biochemical Determinants of Health: Towards a 'Database of Salutogenic Potential'.

Jake M Robinson, Joel Brame, Christian Cando-Dumancela, Sonali Deshmukh, Nicole W Fickling, Scott Hawken, Claire Hayward, Emma Kuhn, Kevin Lee, Craig Liddicoat and 4 more

Abstract read
In one paragraph

Article in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jake M RobinsonCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0001-8108-3271
Joel BrameCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0002-1852-9987
Christian Cando-DumancelaCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0003-0186-0056
Sonali DeshmukhThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.
Nicole W FicklingCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0002-2145-8198
Scott HawkenThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0001-6874-3730
Claire HaywardThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0001-8479-8627
Emma KuhnThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0002-1152-1851
Kevin LeeThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.
Craig LiddicoatCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0002-4812-7524
Sunita RameshCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0003-2230-4737
Kate RobinsonThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.
Xin SunThe Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, South Australia, Australia.
Martin F BreedCollege of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0001-7810-9696

Funding

International Partnership Program of Chinese Academy of Sciences 322GJHZ2022028FNNational Environmental Science ProgramNational Key Research and Development Program of China 2023YFF1304600National Natural Science Foundation of China 32361143523New Zealand Ministry of Business Innovation and Employment UOWX2101
6 · The paper itself

Abstract

Microbial and biochemical research has historically focused on pathogenic agents due to their clear association with disease. This is a perspective that has saved countless lives but encourages a skewed, threat-centered view of microbes and biogenic compounds. Emerging evidence shows that exposure to diverse environmental microbiomes and natural biochemical products is also salutogenic-promoting health and resilience. Here we introduce the 'Database of Salutogenic Potential', a prototype relational repository cataloguing environmental microbes and biochemical compounds linked to health benefits. Drawing from more than 200 articles, we identified 124 potentially salutogenic microbial taxa, 14 biochemical compounds and 63 associated benefits. By creating a structured and open platform, we aim to shift the balance between pathogen-centric and salutogenic perspectives, potentially enabling future applications in public health, urban planning and ecosystem restoration. While the current iteration of the database primarily centers on human health outcomes, it is designed to expand into ecosystem health domains, embedding salutogenic thinking into One Health frameworks. We present this as a first step, not a ready-to-use tool, and invite collaborative refinement from the scientific community.

Indexed as

BacteriaDatabases, FactualEnvironmental MicrobiologyMicrobiotaHumansaerobiomeAIR Hubbioaerosolsbiodiversity hypothesisbiophilic environmentsold friends hypothesisOne Health frameworksalutogenic

Identifiers

PMID41030122
PMCPMC12485223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.