ArticleBrain and behavior2025
Analysis of the Maturation of the Median Nerve in Preterm-Born Children During the First 3 Years of Life Using High-Resolution Nerve Ultrasound Imaging.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association Between Head Circumference Growth and Peripheral Nerve Cross-Sectional Area Growth in Infants: A Potential Future Biomarker for Central and Peripheral Nerve Maturation.Neuropediatrics · 2026Article
- Analysis of the Maturation of the Median Nerve in Preterm-Born Children During the First 3 Years of Life Using High-Resolution Nerve Ultrasound Imaging.Brain and behavior · 2025Article
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Authors and funding
5 authors.
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Abstract
aimTo compare the development of the peripheral nervous systems of preterm- and term-born children from birth to 3 years of age by imaging the median nerve.
methodsMeasuring the cross-sectional area (CSA) of the median nerve at three locations along the arm in term-born (control group) and preterm-born children (study group) using high-resolution ultrasound imaging.
resultsThe data revealed a steady myelination that follows a logarithmic curve when considering the increase of the CSA of the median nerve relative to body surface area (BSA) in preterm-born children. Therefore, while the CSA of the median nerve was smaller in premature babies at the time of birth, the maturation of the nerve is comparable for preterm- and term-born children.
interpretationThis study analyzed how the peripheral nervous system of preterm children develops compared to full-term children and found no differences in terms of median nerve development. Further, these findings align with previous research documenting a logarithmic increase in the CSA of the median nerve with age in full-term infants. This research could be helpful for enabling the use of high-resolution ultrasound imaging as a diagnostic tool for the peripheral nervous system of premature infants.
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