Evidence map›Paper›PMID 41029942›Full record

ArticlePhysiological reports2025

Beyond the shunt: Divergent insights from hyperoxia testing and contrast echocardiography in adults with pulmonary hypertension.

A Beurnier, T Lacoste-Palasset, X Jaïs, L Savale, A Bouchachi, M R Ghigna, S Keddache, A Boucly, F Bauer, O Sitbon and 3 more

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

A BeurnierFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.ORCID 0000-0002-0481-3266
T Lacoste-PalassetFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
X JaïsDepartment of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, FHU André Cournand, ERN-LUNG, Bicêtre Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Le Kremlin-Bicêtre, France.
L SavaleFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
A BouchachiDepartment of Cardiology, Bicêtre Hospital, DMU 4 Correve, Assistance Publique - Hôpitaux de Paris (AP-HP), Le Kremlin-Bicêtre, France.
M R GhignaGustave Roussy Department of Biopathology, Villejuif, France.
S KeddacheDepartement of Physiology-Functional Explorations, DMU 5 Thorinno, bi-Site Bicêtre Hospital (Le Kremlin Bicêtre) and Ambroise Paré Hospital (Boulogne-Billancourt) Hospitals, Assistance Publique - Hôpitaux de Paris (AP-HP), Le Kremlin-Bicêtre, France.
A BouclyFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
F BauerFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
O SitbonFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
M HumbertFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.
M BonayDepartement of Physiology-Functional Explorations, DMU 5 Thorinno, bi-Site Bicêtre Hospital (Le Kremlin Bicêtre) and Ambroise Paré Hospital (Boulogne-Billancourt) Hospitals, Assistance Publique - Hôpitaux de Paris (AP-HP), Le Kremlin-Bicêtre, France.
D MontaniFaculty of Medicine, Université Paris Saclay, Le Kremlin Bicêtre, France.ORCID 0000-0002-9358-6922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to evaluate the agreement between hyperoxia test (HT) and contrast transthoracic echocardiography (CE) for shunt detection in patients with pulmonary hypertension (PH) and unexplained hypoxemia. We retrospectively collected data from consecutive hypoxemic PH patients over a 2-year period. The tests were conducted sequentially, and their agreement was assessed using Cohen's kappa coefficient. Fifty-five PH patients were included, with a median age of 67 years [58-73]; among them, 35 (63.6%) were classified as having pulmonary arterial hypertension (PAH). The mean pulmonary arterial pressure was 39 mmHg [34-49] and pulmonary vascular resistance (PVR) was 5.3 WU [3.8-8.9]. P

Indexed as

EchocardiographyHyperoxiaHypertension, PulmonaryAgedFemaleHumansHypoxiaMaleMiddle AgedRetrospective StudiesVascular Resistancehyperoxiahypoxemiapulmonary hypertensionshunt

Identifiers

PMID41029942
PMCPMC12484305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.