Evidence map›Paper›PMID 41029843›Full record

ArticleMolecular autism2025

Different exploration strategies along the autism spectrum: diverging effects of autism diagnosis and autism traits.

Fien Goetmaeckers, Judith Goris, Jan R Wiersema, Tom Verguts, Senne Braem

Abstract read
In one paragraph

Article in Molecular autism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fien GoetmaeckersDepartment of Experimental Psychology, Ghent University, Henri Dunantlaan 2, Gent, 9000, Belgium. fien.goetmaeckers@ugent.be.
Judith GorisDepartment of Experimental Psychology, Ghent University, Henri Dunantlaan 2, Gent, 9000, Belgium.
Jan R WiersemaDepartment of Experimental Clinical and Health Psychology, Ghent University, Henri Dunantlaan 2, Gent, 9000, Belgium.
Tom VergutsDepartment of Experimental Psychology, Ghent University, Henri Dunantlaan 2, Gent, 9000, Belgium.
Senne BraemDepartment of Experimental Psychology, Ghent University, Henri Dunantlaan 2, Gent, 9000, Belgium.

Funding

FWO fellowship 11E2523NFWO project G010319N
6 · The paper itself

Abstract

backgroundWhen faced with many options to choose from, humans typically need to explore the utility of new choice options. People with an autism diagnosis or elevated autism traits are thought to avoid exploring such unknown options, but it remains unclear how autism affects exploration in decision spaces with many options.

methodsIn a large online sample (N = 588), we investigated the impact of autism diagnosis or elevated autism traits on exploration behavior during value-based decision-making in vast decision spaces. We used a 121-armed bandit with spatially correlated choice options, and a dedicated computational model to disentangle generalization, uncertainty-guided exploration, and random exploration strategies.

resultsOur findings show that participants with a self-reported autism diagnosis were less likely to explore novel choice options and more likely to exploit known high-value options. Computational modeling suggests they engaged in less uncertainty-driven exploration but exhibited equal random exploration and generalization strategies. Interestingly, among non-diagnosed participants, people with elevated autism traits did not explore less. LIMITATIONS: This study relies on self-reported autism diagnoses and trait measures collected online. This may limit the generalizability of the findings to clinically verified or more diverse autism populations.

conclusionsOur findings highlight important differences in exploration strategies between clinical and subclinical populations and emphasize the importance of cognitive modeling and using vast decision spaces to better understand autism.

Indexed as

Autism Spectrum DisorderAutistic DisorderExploratory BehaviorAdolescentAdultChoice BehaviorDecision MakingFemaleHumansMaleUncertaintyYoung AdultAutismComputational cognitive modelingExplorationUncertaintyValue-based decision-making

Identifiers

PMID41029843
PMCPMC12487094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.