ArticleJournal of physiological anthropology2025
Characteristics of cold-induced vasodilation among Tibetans and Han Chinese at high altitudes.
Article in Journal of physiological anthropology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCold-induced vasodilation (CIVD) reduces the risk of local cold injuries. There are obvious differences in CIVD characteristics among different ethnic groups. This study aimed to compare cold tolerance manifested through CIVD responses in indigenous Tibetans and Han residents in Tibet.
methodsA total of 12 Tibetans and 10 Han individuals (residence duration at high altitude > 5 years) from high altitudes were recruited in the study. The CIVD test was performed by immersing the participants' middle finger of the non-dominant hand in cold water (0 ℃) for 30 min followed by recovery for 10 min at a temperature of 25 ± 1 ℃. During the CIVD tests, the participants provided perceptual responses for the immersed hand every 5 min. The participants completed their baseline questionnaires and physiological assessments before the start of the CIVD test, and they completed their hematological tests the following morning.
resultsCompared with Hans at high altitude, Tibetans had higher minimum temperature (T
conclusionCompared with Hans at high altitude, indigenous Tibetans demonstrated superior local cold resistance phenotypes in vasomotor regulation, evidenced by their distinct CIVD and perceptual responses. Hematological and biochemical parameters, erythrocytosis is a critical determinant of local cold tolerance at high altitude in the general population. BAS%, NEU%, and GGT are related to local cold tolerance in Han residents.
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