Evidence map›Paper›PMID 41029659›Full record

ArticleBMC public health2025

Evaluating the effectiveness of lifestyle education for individuals at increased risk of type 2 diabetes and cardiovascular diseases (Halt2Diabetes): protocol for a repeated measures study.

Jorik Vergauwen, Fanny Monnet, Josefien Van Olmen, Edwin Wouters, Katrien Danhieux, Laurent Desmet, Monika Martens, Ruth Verdegem, Justine Vanhaecke, Aurélie Lampaert and 3 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jorik Vergauwen *Department of Sociology, University of Antwerp, Antwerp, Belgium. jorik.vergauwen@uantwerpen.be.
Fanny MonnetDepartment of Sociology, University of Antwerp, Antwerp, Belgium.
Josefien Van OlmenDepartment of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
Edwin WoutersDepartment of Sociology, University of Antwerp, Antwerp, Belgium.
Katrien DanhieuxDepartment of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
Laurent DesmetDepartment of Nursing and Midwifery Sciences, University of Antwerp, Antwerp, Belgium.
Monika MartensDepartment of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
Ruth VerdegemDiabetes Liga, Ghent, Belgium.
Justine VanhaeckeDiabetes Liga, Ghent, Belgium.
Aurélie LampaertDiabetes Liga, Ghent, Belgium.
Sabine VerstraeteDiabetes Liga, Ghent, Belgium.
Inge EveraertDiabetes Liga, Ghent, Belgium.
William Leysen *Diabetes Liga, Ghent, Belgium.

Funding

EU4Health Programme 2021-2027 by the European Union Grant Agreement 101126953
6 · The paper itself

Abstract

backgroundHalt2Diabetes is a prevention initiative in Flanders, Belgium, targeting the rising prevalence of type 2 diabetes (T2D) and cardiovascular diseases (CVDs). The program uses a two-step approach to identify high-risk individuals and guide them towards healthier lifestyles, reducing T2D and CVD risk factors. Building on evidence that lifestyle interventions can prevent both conditions by addressing modifiable risk factors, this research evaluates the effectiveness of Halt2Diabetes as a scalable real-world intervention and its potential as a blueprint for other contexts.

methodsThe Halt2Diabetes program identifies high-risk individuals using the Finnish Diabetes Risk Score (FINDRISC) through an online risk assessment tool. Eligible participants, referred by general practitioners, participate in six group-based lifestyle guidance sessions led by trained dietitians, focusing on healthy eating, physical activity, and behavior modification. This longitudinal study employs repeated measurements at five time points over 18 months. Primary outcomes include changes in body weight, waist circumference, and hemoglobin A1c (HbA1c) levels. Secondary outcomes encompass blood pressure, cholesterol levels, physical activity, and dietary habits. Data collection involves self-reported questionnaires, biochemical measures, and anthropometric assessments. Analysis will examine longitudinal changes in health and behavioral outcomes among participants. DISCUSSION: This study will provide evidence for the real-world effectiveness of Halt2Diabetes in promoting sustained lifestyle changes and reducing T2D and CVD risk factors. Despite challenges including participation barriers and data integration needs, the program's scalable, digitalized risk assessment model shows promise for broader application. The findings will enhance understanding of effective T2D and CVD prevention strategies, offering insights for policymakers and healthcare providers to strengthen public health initiatives.

trial registrationThis study is registered with the ISRCTN registry, identifier: ISRCTN62149214 ( https://www.isrctn.com/ISRCTN62149214 ). The date of registration is March 13, 2025.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Health EducationLife StyleAdultBelgiumExerciseFemaleHumansLongitudinal StudiesMaleMiddle AgedProgram EvaluationRisk AssessmentRisk FactorsCardiovascular diseases (CVDs)Lifestyle interventionLongitudinal studyPreventable diseasesPreventive healthReal-world effectivenessRisk assessmentRisk modificationType 2 diabetes (T2D)

Identifiers

PMID41029659
PMCPMC12486642

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.