Evidence map›Paper›PMID 41029576›Full record

ArticleBMC public health2025

Social determinants of health and biological age among diverse U.S. Adults, NHANES 2011-2018.

Robert A Mesa, Maria M Llabre, David J Lee, Tatjana Rundek, Katrina L Kezios, Adina Zeki Al Hazzouri, Tali Elfassy

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Robert A MesaDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA. ram372@miami.edu.
Maria M LlabreDepartment of Psychology, University of Miami, Miami, FL, USA.
David J LeeDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Tatjana RundekDepartment of Neurology, University of Miami, Miami, FL, USA.
Katrina L KeziosDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Adina Zeki Al HazzouriDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Tali ElfassyKatz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

BEHAVIORAL MEDICINE RESEARCH IN CARDIOVASCULAR DISEASET32HL007426 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI PENEDO, FRANK J · 1985 to 2023
$7.1M
A Multilevel Investigation of Migration and Dementia Risk Among Mexican AmericansR01AG089174 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Medellena Maria Glymour, Adina Zeki Al Hazzouri · 2024 to 2026
$2.5M
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortK99AG084769 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEZIOS, KATRINA L · 2024 to 2025
$263k
NHLBI NIH HHS 5T32HL007426NHLBI NIH HHS T32 HL007426NIA NIH HHS K99 AG084769NIA NIH HHS K99AG084769NIA NIH HHS R01 AG089174NIA NIH HHS R01AG089174
6 · The paper itself

Abstract

backgroundSocial determinants of health are fundamental drivers of health inequities. Education and income are inversely associated with accelerated aging, but less is known about differences in their association with aging by race/ethnicity. We examined the sex-specific association between each social determinant of health with biological age and by race/ethnicity.

methodsData were sourced from four two-year National Health and Nutrition Examination Survey cycles (2011–2018). Education and household income were self-reported. The Klemera-Doubal Method, an algorithm using biomarkers from different organ systems, was used to calculate biological age among 6,213 females and 5,938 males aged 30–75 years who were Mexican, other Hispanic, non-Hispanic White, non-Hispanic Black, non-Hispanic Asian, or other/multi-racial. We used multivariable linear regression models to determine the association between education and income and biological age.

resultsCompared with a college education, less than a high school education was associated with higher biological age by 3.17 years (95% CI: 1.69, 4.65) among females only; associations were strongest among non-Hispanic Black, other Hispanic, and non-Hispanic Asian female adults. Compared with an annual income of ≥$75,000, an income <$25,000 was associated with higher biological age by 4.94 years (95% CI: 3.40, 6.47) among males and 2.74 years among females (95% CI: 1.48, 4.00); associations were strongest among non-Hispanic White and non-Hispanic Asian adults, and Mexican and other Hispanic males.

conclusionsThese findings demonstrate that adverse levels of education and income are associated with greater biological age among females and males, and racial/ethnic minority adults in particular. Targeting upstream sources of social disadvantage among racial/ethnic minority groups, in conjunction with improvements to income and education, may promote healthy aging in these populations.

Indexed as

AgingEthnicityRacial GroupsSocial Determinants of HealthAdultAgedAsianBlack or African AmericanEducational StatusFemaleHumansIncomeMaleMiddle AgedNutrition SurveysSex FactorsAccelerated agingHealth equityHealthy agingRacial/ethnic minority populationsSocial determinants of health

Identifiers

PMID41029576
PMCPMC12486641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.