Evidence map›Paper›PMID 41029567›Full record

SynthesisBMC pregnancy and childbirth2025

Magnitude and predictors of gestational trophoblastic disease in East Africa: a systematic review and meta-analysis.

Gizachew Yilak, Befkad Derese Tilahun, Amsalu Baylie Taye, Bogale Molla, Addisu Getie, Dejen Tsegaye, Mulat Ayele, Eyob Shitie Lake

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Gizachew YilakDepartment of Nursing, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia. gyilak9@gmail.com.
Befkad Derese TilahunDepartment of Nursing, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia.
Amsalu Baylie TayeDepartment of Nursing, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia.
Bogale MollaDepartment of Nursing, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia.
Addisu GetieDepartment of Nursing, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Dejen TsegayeDepartment of Nursing, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Mulat AyeleDepartment of Midwifery, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia.
Eyob Shitie LakeDepartment of Midwifery, College of Health Sciences, Woldia University, P.O.Box: 400, Woldia, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGestational Trophoblastic Disease (GTD) encompasses a spectrum of placenta-related disorders with significant health risks. Despite the varying reported prevalence rates in East Africa, no comprehensive meta-analysis has been conducted to synthesize the overall burden and predictors of GTD in this region.

methodsFollowing the PRISMA guidelines, we conducted a systematic review and meta-analysis of studies from PubMed, Cochrane Library, and Google Scholar (search period: 2000-2024). We assessed heterogeneity (I

resultsEleven studies were included, revealing a pooled GTD magnitude of 10.5% (95% CI: 8.8-12.3; I

conclusionGestational trophoblastic disease remains a significant public health burden in East Africa, where delayed healthcare access contributes to worsened outcomes. Women with a history of gestational trophoblastic disease or high parity constitute high-risk populations that require targeted screening programs and early intervention strategies to improve their detection and management.

Indexed as

Gestational Trophoblastic DiseaseAfrica, EasternFemaleHumansHydatidiform MolePregnancyPrevalenceRisk FactorsChoriocarcinomaEast AfricaGestational trophoblastic diseaseHydatidiform moleMolar pregnancy

Identifiers

PMID41029567
PMCPMC12487570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.