Evidence map›Paper›PMID 41029559›Full record

ArticleBMC ophthalmology2025

Characteristics of geographic atrophy secondary to age-related macular degeneration in Korean patients.

Sang Min Park, Daeun Shin, Chul Gu Kim, Jae Hui Kim

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Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Sang Min Park *Department of Ophthalmology, Kim's Eye Hospital, #156 Youngdeungpo-dong 4ga, Youngdeungpo-gu, Seoul, 150-034, South Korea.
Daeun Shin *Department of Ophthalmology, Kim's Eye Hospital, #156 Youngdeungpo-dong 4ga, Youngdeungpo-gu, Seoul, 150-034, South Korea.
Chul Gu KimDepartment of Ophthalmology, Kim's Eye Hospital, #156 Youngdeungpo-dong 4ga, Youngdeungpo-gu, Seoul, 150-034, South Korea.
Jae Hui KimDepartment of Ophthalmology, Kim's Eye Hospital, #156 Youngdeungpo-dong 4ga, Youngdeungpo-gu, Seoul, 150-034, South Korea. kimoph@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the characteristics of geographic atrophy (GA) in the Korean population and investigate the factors associated with visual acuity.

methodsPatients with complete retinal pigment epithelium and outer retinal atrophy were considered to have GA. The characteristics of GA, including lesion type (monofocal or multifocal), total lesion size, foveal involvement, best-corrected visual acuity, and subfoveal choroidal thickness (SCT), were evaluated. The incidence of pachychoroid GA and factors associated with better visual acuity (≥ 20/40) were also determined.

resultsThis study included 104 eyes of 68 patients with a mean age of 77.6 ± 7.0 years. Bilateral GA was detected in 52.9% of patients. Monofocal and multifocal lesions were observed in 49% and 51% of the eyes, respectively. The mean lesion size was 9.9 ± 8.9 mm². Foveal involvement was observed in 41.3% of eyes. The mean SCT was 154.6 ± 90.1 μm, and pachychoroid GA was detected in 7.7% of eyes. Greater central retinal thickness and the absence of foveal involvement were associated with better visual acuity.

conclusionsThe prevalence of bilateral GA and larger lesions were higher while the prevalence of pachychoroid GA was lower among our patients than among those included in previous studies involving East Asian populations. This study highlights the diverse characteristics of GA in Koreans and suggests that patients with GA characteristics comparable to those observed in Western populations may be frequently encountered depending on the center.

Indexed as

Geographic AtrophyMacular DegenerationAgedAged, 80 and overChoroidFemaleFluorescein AngiographyHumansIncidenceMalePrevalenceRepublic of KoreaRetinal Pigment EpitheliumRetrospective StudiesTomography, Optical CoherenceVisual AcuityAge-related macular degenerationGeographic atrophyKoreanRetinal pigment epithelial atrophy

Identifiers

PMID41029559
PMCPMC12487059

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