ArticleBMC pregnancy and childbirth2025
Angiogenesis and endometrial receptivity in the decidua of cesarean scar pregnancies.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCesarean scar pregnancy (CSP) is defined as a gestational sac or trophoblast implanted within the previous cesarean scar (CS). This study aimed to investigate the mechanism of CSP.
methodsWe collected the decidual tissues from the cesarean scar (n = 25) and the uterine cavity (n = 25) of the same women at the department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology from July to December 2023. We examined the morphological changes and angiogenesis in the decidual tissues and investigated the expression of factors related to endometrial recovery. Scanning electron microscope was used to detect the number of pinopodes.
resultsCompared to the CSP-cesarean cavity group, the CSP-uterine scar group exhibited more diffuse lymphocyte infiltration in the decidual tissues. The vessel density (31.95 vessels/mm
conclusionsCesarean scar decidual tissues exhibit reduced angiogenesis and endometrial receptivity. The altered vascular patterns in cesarean scar decidual tissues may facilitate embryo implantation.
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