Evidence map›Paper›PMID 41029351›Full record

ArticleBMC complementary medicine and therapies2025

Herbal medicines and blood pressure control among hypertensive individuals across two of trinidad's regional health facilities.

A F Williams-Persad, G Carvalho, S Baboolal, A Brereton, K Chinemilly, M Premchand, R Ramdial, A Ramroop, P Richards, T Seepersad

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Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

A F Williams-PersadDepartment of Pathology/Microbiology and Pharmacology, School of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago. arlene.williams@sta.uwi.edu.
G CarvalhoSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
S BaboolalSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
A BreretonSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
K ChinemillySchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
M PremchandSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
R RamdialSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
A RamroopSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
P RichardsSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.
T SeepersadSchool of Medicine, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, St. Augustine, Trinidad & Tobago.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-medication with herbal medicine (HM) to manage hypertension is an expanding trend worldwide. There is very little evidence to substantiate the motives for use in the control of blood pressure (BP). This study aims to ascertain the relationship between HM and antihypertensive treatment to manage hypertension across two regional health facilities in Trinidad.

methodsThis cross-sectional investigation surveyed hypertensive patients aged 35-64 from the North-Central and Eastern Regional Health facilities across Trinidad. Consent was obtained from 139 participants through convenience sampling. Data collection was obtained using a questionnaire designed and developed by the research team, included a self-reporting questions and patient medical records sections. Data was analysed using Chi-square and Mann-Whitney U tests for non-normally distributed variables, with statistical significance set at a 95% confidence interval.

resultsHM-users were either hypertensive stage 1 or 2 with no significant correlation between BMI and hypertensive stage (p-value = -0.053, p-value = 0.537). Garlic (Allium sativum L) (57%), most used as a tea, was taken daily 'to control BP'. The current systolic and diastolic blood pressures were not significantly different between HM-users and non-users. Among herbal medicine users, 15.7% achieved blood pressure control compared to 30.4% for non-users. Patients using herbal medicine (84.3%) were more likely to have uncontrolled blood pressure (p-value < 0.05), supported by a negative correlation (phi = -0.175) and an odds ratio (95% CI) of 0.426 (0.187-0.969). Patient non-concordance to conventional medication was found to be higher among HM-users identified by the negative association among patients with uncontrolled BP. However, there was no statistically significant difference in non-concordance between HM users (40%) and non-users (29.6%). Antihypertensives prescribed included calcium channel blockers (70.1%), ACE inhibitors (46.3%), and angiotensin-II receptor blockers (40.6%). The most used herb, A. sativum, was preferred for BP control, however, this study showed no significant changes in BP compared to non-users.

conclusionPatient medication concordance is imperative. Herb-drug interactions may be associated with the higher prevalence of patients at hypertensive stages 1 and 2 that are uncontrolled in this study.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionPhytotherapyAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTrinidad and TobagoAntihypertensive AgentsDietary and herbal supplementsHerbal medicinesHypertension

Identifiers

PMID41029351
PMCPMC12482603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.