Evidence map›Paper›PMID 41029312›Full record

ReviewBMC ophthalmology2025

Autoimmune retinopathy in patients with myasthenia gravis: cases series and literature review.

Yiqiao Chen, Yexin Zhang, Jia Luo, Miaomiao Liu, Min Lin, Wenhua Zhu, Wenjun Xiong, Peiquan Zhao, Jianying Xi, Ping Fei

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Yiqiao Chen *Department of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yexin Zhang *Department of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Jia Luo *Department of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Miaomiao LiuDepartment of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Min LinDepartment of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenhua ZhuDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Wenjun XiongDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Peiquan ZhaoDepartment of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jianying XiDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China. xijianying@fudan.edu.cn.
Ping FeiDepartment of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. feiping@xinhuamed.com.cn.

Funding

Hospital Funded Clinical Research, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 24XHCR03BNational Natural Science Foundation of China No. 81770963Open Project of Sichuan Provincial Key Laboratory for Human Disease Gene Study 2023kflx001
6 · The paper itself

Abstract

backgroundPrevious studies showed a higher frequency of concurrent autoimmune disease (AD) in patients with Myasthenia gravis (MG), but very few cases on MG patients complicated with AIR have been reported in preview literature. The goal of this study was to present three cases of autoimmune retinopathy (AIR) with myasthenia gravis (MG), conduct a literature search, and summarize the clinical characteristics of this entity.

methodsCase series and literature review.

resultsThe seven AIR patients with MG were six females and a male with a mean age of 41.29(± 15.22)years old. Five had thymoma, and two had no tumor. Their symptoms of MG improved after treatment. The main ocular manifestations of AIR were bilateral, subacute, painless vision loss. The fundus examinations showed diffuse pigmentary retinopathy and atrophy of retina. Electroretinography (ERG) showed dysfunction of rod and cone cell. Hereditary retinopathy was ruled out. ARA (anti-retinal antibody) testing showed positive result for anti-retinal antibodies (ARAs), confirming the diagnosis of AIR.

conclusionsThere is a certain frequency of concurrent MG and AIR. Patients with AIR have distinct features in the course of the disease, multimodal auxiliary examination and ARA testing. Suspected cases of MG should be comprehensively screened for early diagnosis and treatment of AIR.

Indexed as

Autoimmune DiseasesMyasthenia GravisRetinal DiseasesAdultAutoantibodiesElectroretinographyFemaleHumansMaleMiddle AgedAutoantibodiesAnti-retinal antibodiesAutoimmune retinopathyCancer-associated retinopathyMyasthenia gravisThymoma

Identifiers

PMID41029312
PMCPMC12487295

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.