SynthesisBMC pregnancy and childbirth2025
Adverse birth outcomes and associated factors among African grand multiparous women: a systematic review and meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Correlates of self-reported pregnancy complications: a cross-sectional study in two districts in Northern Ghana.Archives of public health = Archives belges de sante publique · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdverse birth outcomes linked to grand multiparity are often more complex than those associated with multiparity. The primary literature on this issue reveals inconsistent findings across various studies. There is a paucity of data in systematic reviews and meta-analyses that specifically assess adverse birth outcomes in African grand multiparas.
objectivesTo determine the pooled adverse birth outcomes and their associated factors among multiparous women in Africa.
methodsPubMed/Medline, Scopus, Web of Science, ScienceDirect, African Journal Online, Google Scholar, and Wiley Online Library were searched between April 20, 2024, and June 15, 2024. The Newcastle-Ottawa Scale was used to assess methodological quality. Data extraction was performed using Excel, and analysis was conducted with Stata 11 software. Cochran’s Q test and the I² statistic assessed study heterogeneity. Subgroup analysis was conducted based on publication years, and sample sizes. Publication bias was evaluated using funnel plot symmetry and Egger’s test. The prevalence of adverse birth outcomes was estimated using a Random Effects Model, and odds ratios (ORs) with 95% confidence intervals (CIs) were used to pool associated factors.
resultsEighteen studies met the eligibility criteria with a total sample size of 27,122 study participants. The pooled prevalence of adverse birth outcomes among African grand multiparas was 24.97%), 95% CI: 19.97, 31.99). Rural residence (AOR: 4.12; 95% CI: 3.12, 5.44), a history of home births (AOR: 3.30; 95% CI: 1.70, 6.40), and pregnancy-related complications (AOR: 3.17; 95% CI: 2.35, 4.28) were significantly associated with adverse birth outcomes among African grand multiparas women.
conclusionsOverall, the pooled prevalence of adverse birth outcomes among grand multiparas was comparably high. Variables such as rural residence, previous pregnancy-related complications, and a history of home births were significantly associated with adverse birth outcomes. Strengthening institutional births, providing high-quality prenatal care, and early pregnancy follow-ups are recommended to reduce adverse birth outcomes in grand multipara women. Additionally, improving the availability of comprehensive contraceptive options for rural-residing African grand multipara women is essential. PROSPERO Registration: CRD42024569768.
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