Evidence map›Paper›PMID 41029196›Full record

Trial reportBMC medical research methodology2025

BRIDGe recruitment strategies for frail older adults in intervention trials: lessons learned from the ACTIVE-AGE@home trial.

Jade Tambeur, Emma De Keyser, Elke De Smedt, Dimitri Vrancken, Lieven Annemans, David Beckwée, Wim Peersman, Siddhartha Lieten, Dominique Van de Velde, Patricia De Vriendt

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medical research methodology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05946109 (Tackling FRAILTY), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05946109 narecruitingnot on this map

Tackling FRAILTY: ACTIVE-AGE@home: a Home-based Functional Exercise Program for Community Dwelling Frail Older Adults Provided by Professionals and Volunteers.

TypeinterventionalSponsorUniversitair Ziekenhuis BrusselRan2023 to 2026Enrolled195ConditionsFrailtyArmsACTIVE-AGE@home
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jade Tambeur *Department of gerontology, Frailty in Ageing Research Group (FRIA), Mental Health and Wellbeing Research Group (MENT), Vrije Universiteit Brussel, Laarbeeklaan, 103, Brussel, 1090, Belgium. jade.helene.tambeur@vub.be.
Emma De Keyser *Department of gerontology, Frailty in Ageing Research Group (FRIA), Mental Health and Wellbeing Research Group (MENT), Vrije Universiteit Brussel, Laarbeeklaan, 103, Brussel, 1090, Belgium.
Elke De SmedtGeriatrics department, University Hospital of Brussels , Brussels, Belgium.
Dimitri VranckenDepartment of gerontology, Frailty in Ageing Research Group (FRIA), Mental Health and Wellbeing Research Group (MENT), Vrije Universiteit Brussel, Laarbeeklaan, 103, Brussel, 1090, Belgium.
Lieven AnnemansDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.
David BeckwéeDepartment of Rehabilitation Sciences and Physiotherapy, Research group MOVANT, University of Antwerp, Antwerp, Belgium.
Wim PeersmanDepartment of Rehabilitation Sciences, Occupational therapy research group, Ghent University, Ghent, Belgium.
Siddhartha LietenGeriatrics department, University Hospital of Brussels , Brussels, Belgium.
Dominique Van de VeldeDepartment of Rehabilitation Sciences, Occupational therapy research group, Ghent University, Ghent, Belgium.
Patricia De VriendtDepartment of gerontology, Frailty in Ageing Research Group (FRIA), Mental Health and Wellbeing Research Group (MENT), Vrije Universiteit Brussel, Laarbeeklaan, 103, Brussel, 1090, Belgium.

Funding

Fonds Wetenschappelijk Onderzoek grant number: T002322N
6 · The paper itself

Abstract

backgroundRecruiting frail older adults is challenging, resulting in underpowered trials, wasted resources, and unexpected costs. Researchers rarely report transparently and comprehensively on recruitment. However, sharing recruitment experiences could improve future efforts. This study tracks recruitment efforts and assesses their impact on recruitment outcomes in the ACTIVE-AGE@home trial to develop effective strategies for engaging community-dwelling frail older adults in long-term trials. 

methodsA mixed-method study assessed recruitment partner contacts and their respective influence on recruitment outcomes at three levels: macro-, meso-, and micro-level contacts. Quantitative data were used to measure strategy efficiency. Qualitative data consisted of field notes, personal annotations recorded by the researchers during 15 months recruitment for ACTIVE-AGE@home. These notes were analyzed thematically following Braun and Clarke’s approach: deductively, guided by the TIBaR model for recruiting hard-to-reach older adults (emphasizing building Trust, offering Incentives, identifying Barriers, and being Responsive), and inductively to explore themes related to prolonged engagement, adherence and maintenance. 

resultsOver 15 months, 49 macro-level, 112 meso-level, and 1001 micro-level recruitment partners were contacted. Of these, 30 meso-level and 44 micro-level partners referred frail older adults. Micro-level referrals yielded the greatest number of eligible participants, with 6 (meso-level) and 23 ( micro-level) included. The study introduced the “BRIDGe recruitment model” with the following themes: (1) being appealing (2), fostering reciprocal relationships (3), understanding the recruitment partner and target group identity, and (4) gear trial requirements. The BRIDGe model serves as a reflective tool to balance recruitment and identity needs with trial requirements. 

conclusionsMicro-level recruitment strategies are crucial for reaching frail older adults through warm referrals and personal contact. A bottom-up approach targeting local healthcare and welfare workers is recommended, with macro- and meso-level contacts supporting these connections. Rigid study designs hinder recruitment and translating research into practice requires flexible methods. Therefore, balancing rigor and feasibility is essential when designing context-specific studies. By transparently sharing recruitment successes and challenges, we aim to build collective knowledge to overcome recruitment barriers for frail older adults in intervention trials.

trial registrationThe ACTIVEAGE@home trial was registered on ClinicalTrials.gov on July 6, 2023, and published July 14, 2023. Trial registration NCT05946109.

Indexed as

Frail ElderlyPatient SelectionAgedAged, 80 and overFemaleHumansIndependent LivingMaleClinical trialFrailtyOlder adultsParticipationRecruitment strategyResearch design

Identifiers

PMID41029196
PMCPMC12482242

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.