Evidence map›Paper›PMID 41029180›Full record

ArticleGut microbes2025

Shared environments can facilitate microbial transmission and alter metabolic outcomes.

Isin Y Comba, Suzie Hoops, Lisa Till, P J Vangay, Stephen Johnson, Yang Xiao, Tijs Louwies, Kathie Culhane Pera, Shannon Pergament, Dan Knights and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isin Y CombaDivision of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, MN, USA.
Suzie HoopsDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA.
Lisa TillDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
P J VangayBioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, MN, USA.
Stephen JohnsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Yang XiaoDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Tijs LouwiesDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Kathie Culhane PeraSolahmo Partnership for Health and Wellness, Community-University Health Care Center, Minneapolis, MN, USA.
Shannon PergamentSolahmo Partnership for Health and Wellness, Community-University Health Care Center, Minneapolis, MN, USA.
Dan KnightsDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA.
Purna C KashyapDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

Funding

Mechanisms of alteration of GI physiology by gut microbesR01DK114007 · NIDDK · MAYO CLINIC ROCHESTER · PI Purna C Kashyap · 2017 to 2026
$4.7M
NIDDK NIH HHS R01 DK114007
6 · The paper itself

Abstract

While dietary changes are often implicated in the adaptation of traditional microbiomes to highly industrialized society, it only partially explains the observed microbial shifts post-immigration. Here, we used germ-free mice colonized with human donor stool from the United States and Thailand to investigate how person-to-person transmission of gut commensals - via shared air and physical contact - affects U.S. and Thai microbiomes and subsequent health outcomes. We found that both air sharing and physical contact enabled bidirectional transmission: U.S. mucus-degrading taxa (e.g.,

Indexed as

BacteriaGastrointestinal MicrobiomeAnimalsDietFecesFemaleHumansMaleMiceMice, Inbred C57BLThailandUnited StatesAkkermansiafood additivesgut microbiomeImmigrationindustrializationLactobacillusmicrobiome transmissionnon-nutritive sweeteners

Identifiers

PMID41029180
PMCPMC12489994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.