SynthesisActa ophthalmologica2026
Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta-analysis.
Synthesis in Acta ophthalmologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between central serous chorioretinopathy and personality types: A systematic review and meta-analysis.Acta ophthalmologica · 2026Pooled it
- Clinical and multimodal imaging characteristics of acute central serous chorioretinopathy with fibrinous exudation.International journal of ophthalmology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta-analysis to obtain a summary estimate.
methodsWe searched 12 literature databases on 16 February 2025 for epidemiological studies, which evaluated the potential association between pregnancy and CSC. All eligible studies were included for a qualitative review and a meta-analysis. The meta-analysis was made using the random-effects model on the odds ratio (OR) of the association between pregnancy and CSC.
resultsFour studies were eligible for our review. Of the 2766 individuals (1345 patients with CSC, 1391 controls) in these studies, females constituted 26%-64% of study populations in individual studies. The calculated summary estimate of pregnancy as a risk factor for CSC was OR 5.51 (95% CI: 2.12-14.30, p = 0.00046). Heterogeneity statistics suggested minimal to no heterogeneity (Cochran's Q = 0.72; I
conclusionPregnancy appears to be a significant risk factor for CSC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.