Evidence map›Paper›PMID 41028823›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Identifying optimal positive end-expiratory pressure with electrical impedance tomography guidance in severe bronchopulmonary dysplasia.

Jessica E Shui, Carolyn J LaVita, Glasiele C Alcala, John H Nichols, Romal K Jassar, Rodica M Turcu, Paul H Lerou, Maurizio F Cereda, Ryan W Carroll, Roberta Ribeiro De Santis Santiago and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jessica E Shui *Division of Newborn Medicine, Mass General Brigham for Children, Boston, MA, USA. Jshui@Mgh.Harvard.Edu.ORCID http://orcid.org/0000-0003-1933-3174
Carolyn J LaVita *Department of Respiratory Care, Massachusetts General Hospital, Boston, MA, USA.
Glasiele C AlcalaDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
John H NicholsHarvard Medical School, Boston, MA, USA.
Romal K JassarDivision of Newborn Medicine, Mass General Brigham for Children, Boston, MA, USA.
Rodica M TurcuDivision of Newborn Medicine, Mass General Brigham for Children, Boston, MA, USA.ORCID http://orcid.org/0009-0009-6621-7468
Paul H LerouDivision of Newborn Medicine, Mass General Brigham for Children, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6777-7389
Maurizio F CeredaHarvard Medical School, Boston, MA, USA.
Ryan W CarrollHarvard Medical School, Boston, MA, USA.
Roberta Ribeiro De Santis SantiagoDepartment of Respiratory Care, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5818-0361
Lorenzo BerraHarvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the feasibility of electrical impedance tomography (EIT) guided positive end-expiratory pressure (PEEP) titration to identify optimal PEEP in infants with severe bronchopulmonary dysplasia (BPD). STUDY

designCase series of five EIT guided PEEP titrations in infants with severe BPD compared to a case series of five infants, without lung disease, requiring intubation. Optimal PEEP was identified as minimal percentage of lung overdistension and collapse. Lung function, bedside ventilatory and clinical data were tracked post EIT guided optimal PEEP titration.

resultFour out of the five EIT assessments in infants with BPD identified an optimal PEEP that was sustained for at least three weeks. Three of the four successful assessments led to a decrease in PEEP, compared to baseline, and one confirmed the baseline PEEP was optimal.

conclusionEIT assessments can be a novel tool to aide identification of optimal PEEP in infants with heterogeneous lung disease.

Indexed as

Bronchopulmonary DysplasiaElectric ImpedancePositive-Pressure RespirationTomographyFeasibility StudiesFemaleHumansInfantInfant, NewbornInfant, PrematureMale

Identifiers

PMID41028823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.