Evidence map›Paper›PMID 41028641›Full record

ArticleAnnals of surgical oncology2025

Quality of Life in Oropharyngeal Cancer: A Retrospective Analysis of Patient Characteristics and Treatment Modalities.

Ji Won Kim, Bon Seok Koo, Han Su Kim, Jae Hong Park, Jung Je Park, Jun-Ook Park, Jun Girl Seok, Kyoung-Ho Oh, Seung Hoon Woo, Young-Gyu Eun and 9 more

Abstract read
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In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ji Won Kim *Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea.
Bon Seok Koo *Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea.
Han Su KimDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Ewha Womans University, Yangcheon-gu, Seoul, Republic of Korea.
Jae Hong ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Jung Je ParkDepartment of Otolaryngology, Institute of Health Sciences, College of Medicine, Gyeongsang National University, Gyeongsang National University Hospital, Jinju, Republic of Korea.
Jun-Ook ParkDepartment of Otolaryngology-Head and Neck Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jun Girl SeokDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Kyoung-Ho OhDepartment of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, Ansan, Korea.
Seung Hoon WooDepartment of Otorhinolaryngology-Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Korea.
Young-Gyu EunDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.
Yoon Se LeeDepartment of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-Gu, Seoul, Republic of Korea.
Man Ki ChungDepartment of Otorhinolaryngology, Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Woo-Jin JeongDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Eun-Jae ChungDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Yong Bae JiDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Su-Yeon YuDepartment of Pharmacy, College of Pharmacy, Kangwon National University, Chuncheon, Republic of Korea.
Soo Hyun LeeDepartment of Medical Information, College of Nursing and Public Health, Kongju National University, Kongju, Republic of Korea.
Sei Young LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea. syleemd@cau.ac.kr.
Kwang-Jae ChoDepartment of Otolaryngology-Head and Neck Surgery, Catholic University College of Medicine, The Catholic University of Korea, Seoul, Korea. entckj@catholic.ac.kr.

Funding

Korea Disease Control and Prevention Agency 2023-10-012
6 · The paper itself

Abstract

backgroundIn patients with oropharyngeal squamous cell carcinoma (OPSCC), understanding the factors affecting post-treatment quality of life (QoL) is essential for optimizing long-term management. This study aimed to evaluate the impact of patient characteristics and treatment modalities on post-treatment QoL in patients with OPSCC. PATIENTS AND

methodsA total of 303 patients with OPSCC who completed treatment were assessed for QoL between August 2023 and January 2024 using various validated questionnaires. In addition, patient charts were reviewed.

resultsLower QoL was associated with older age, female sex, lower education, reduced income, fewer household members, unemployment, less than 5 years since diagnosis, advanced stage, disease recurrence, and human papillomavirus (HPV)-negative status. Robotic surgery and surgery alone were associated with better QoL than conventional surgery or surgery with adjuvant therapy. Radiotherapy is associated with additional issues, such as dry mouth and sticky saliva. Fewer patients who underwent surgery with adjuvant therapy reported tooth and dry mouth issues than those who received definitive chemoradiotherapy. In subgroup analyses, QoL in HPV-positive patients mirrored that of the overall cohort, whereas no significant differences were noted between treatment modalities in HPV-negative patients. Similarly, in the early stage group, HPV-positive patients had better QoL than HPV-negative patients; however, no significant differences were observed on the basis of HPV status or treatment modality in advanced-stage patients.

conclusionsSociodemographic factors, clinicopathological characteristics, and treatment modalities significantly impacted the post-treatment QoL of patients with OPSCC. Individualized treatment planning and comprehensive post-treatment care are crucial for optimizing QoL, particularly in patients at higher risk of poorer outcomes.

Indexed as

Oropharyngeal NeoplasmsQuality of LifeSquamous Cell Carcinoma of Head and NeckAdultAgedAged, 80 and overChemoradiotherapyCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedPapillomavirus InfectionsPrognosisRetrospective StudiesHuman papillomavirusOropharyngeal squamous cell carcinomaQuality of lifeSurvivorshipTreatment modalities

Identifiers

PMID41028641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.