Evidence map›Paper›PMID 41028567›Full record

Trial reportLasers in medical science2025

Dose-response and efficacy of 660-nanometer low-level laser therapy in healing diabetic foot ulcers: a randomized, double-blind, clinical trial.

Mariana Bezerra Miranda, Ana Carolina Silva Barros, Lorena Veloso Coelho, Rebeca Barbosa da Rocha, Baldomero Antonio Kato da Silva, Fuad Ahmad Hazime, Alessandra Tanuri Magalhães, Vinicius Saura Cardoso

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana Bezerra MirandaPostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil.
Ana Carolina Silva BarrosPostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil.
Lorena Veloso CoelhoBiosignal Laboratory, Parnaíba Delta Federal University (UFDPar),, Parnaíba, Brazil.
Rebeca Barbosa da RochaPostgraduate program in Biotechnology, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil.
Baldomero Antonio Kato da SilvaPostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil.
Fuad Ahmad HazimePostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil.
Alessandra Tanuri MagalhãesBiosignal Laboratory, Parnaíba Delta Federal University (UFDPar),, Parnaíba, Brazil.
Vinicius Saura CardosoPostgraduate program in Biomedical Sciences, Parnaíba Delta Federal University (UFDPar), Parnaíba, Brazil. vscfisio@ufdpar.edu.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic foot ulcers (DFU) negatively impact the quality of life and increase the risk of morbidity and mortality. Although photobiomodulation (PBM) produces better results in DFU healing than standard treatment or in the absence of irradiation, the ideal parameters are not standardized. This study aimed to evaluate the effect of PBM at a wavelength of 660 nm on reducing the DFU area. We compared the PBM treatment of non-infected DFUs. The sessions were held twice a week on non-consecutive days for 10 weeks (20 interventions) using HeNe 660 nm, 20 mW, in continuous mode, with three energy densities (4 J/cm

Indexed as

Diabetic FootLow-Level Light TherapyWound HealingAdultAgedDose-Response Relationship, RadiationDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment OutcomeDiabetic foot ulcersInfrared lightPhotobiomodulationRed light

Identifiers

PMID41028567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.