Evidence map›Paper›PMID 41028544›Full record

ArticleNature medicine2025

Dietary profiles and associated metabolic risk factors in India from the ICMR-INDIAB survey-21.

Ranjit Mohan Anjana, Vasudevan Sudha, Kuzhandaivelu Abirami, Rajagopal Gayathri, Valangaiman Sriram Manasa, Mohan Deepa, Rajendra Pradeepa, Ranjit Unnikrishnan, Shashank Joshi, Banshi Saboo and 18 more

Abstract read
In one paragraph

Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Observational
  14. Article
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  16. Optimizing Continuous Glucose Monitoring Adoption in India: From Current Challenges to Future Solutions.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  17. Article
  18. Article
  19. Genome editing ofCurrent research in food science · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Ranjit Mohan Anjana *Department of Diabetology, Madras Diabetes Research Foundation, Chennai, India. dranjana@drmohans.com.ORCID http://orcid.org/0000-0002-4843-1374
Vasudevan Sudha *Department of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.
Kuzhandaivelu AbiramiDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.
Rajagopal GayathriDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0000-0002-6195-8584
Valangaiman Sriram ManasaDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0009-0005-3019-789X
Mohan DeepaDepartment of Epidemiology, Madras Diabetes Research Foundation, Chennai, India.
Rajendra PradeepaDepartment of Research Operations and Diabetes Complications, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0000-0002-4909-3733
Ranjit UnnikrishnanDepartment of Diabetology, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0000-0002-8587-8861
Shashank JoshiDepartment of Diabetology and Endocrinology, Lilavati Hospital and Research Centre, Mumbai, India.
Banshi SabooDia Care-Diabetes Care and Hormone Clinic, Ahmedabad, India.
Arvind GuptaDepartment of Diabetes, Obesity and Metabolic Disorders, Rajasthan Hospital, Jaipur, India.ORCID http://orcid.org/0000-0001-9828-8732
Prashant P JoshiDepartment of General Medicine, All India Institute of Medical Sciences, Nagpur, India.
Prabha AdhikariDepartment of Epidemiology, Yenepoya Medical College, Yenepoya University Campus, Deralakatte, India.
Puthiyaveettil Kottayam JabbarDepartment of Endocrinology, Government Medical College, Trivandrum, India.
Sunil M JainTOTALL Diabetes Thyroid Hormone Research Institute Pvt. Ltd., Indore, India.
Subhankar ChowdhuryDepartment of Endocrinology and Metabolism, Institute of Post Graduate Medical Education and Research (IPGMER) and SSKM Hospital, Kolkata, India.
Anil J PurtyPondicherry Institute of Medical Sciences, Puducherry, India.
Saroj Kumar TripathyS.C.B. Medical College and Hospital, Cuttack, India.
Sarita BeheraDepartment of Medicine, Bhima Bhoi Medical College and Hospital, Balangir, India.
Jagdish MahantaRegional Medical Research Centre, Dibrugarh, India.
Avula LaxmaiahDivision of Public Health Nutrition, National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India.
Kamala KrishnaswamyDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.
Anura Viswanath KurpadDepartment of Physiology, St. John's Medical College, Bengaluru, India.ORCID http://orcid.org/0000-0001-7998-2438
Ashok Kumar DasDepartment of Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, India.
Rupinder Singh DhaliwalNon-Communicable Disease Division, Indian Council of Medical Research, New Delhi, India.ORCID http://orcid.org/0000-0002-6011-0346
Tanvir KaurNon-Communicable Disease Division, Indian Council of Medical Research, New Delhi, India.
Shilpa N BhupathirajuDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0000-0003-0173-9248
Viswanathan MohanDepartment of Diabetology, Madras Diabetes Research Foundation, Chennai, India.ORCID http://orcid.org/0000-0001-5038-6210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid dietary transitions in India have been associated with an alarming rise in cardiometabolic diseases. Using data from the national Indian Council of Medical Research-India Diabetes survey (18,090 adults), we examined India's dietary profile and the effect of isocaloric substitution of carbohydrates with other macronutrients on metabolic risk. Indian diets are characterized by high intakes of low-quality carbohydrates (white rice, milled whole grains and added sugar), high levels of saturated fat and low intakes of protein. Compared to those with the least carbohydrate intakes, those with the highest intakes had higher risk of newly diagnosed type 2 diabetes (T2D; odds ratio (OR) = 1.30, 95% confidence interval (CI) = 1.14,1.47), prediabetes (OR = 1.20, 95% CI = 1.06,1.33), generalized obesity (OR = 1.22, 95% CI = 1.07,1.37) and abdominal obesity (OR = 1.15, 95% CI = 1.01, 1.30). Replacing refined cereals with whole wheat or millet flour without decreasing overall carbohydrate quantity was not associated with lower risk for T2D (OR = 0.94, 95% CI = 0.57, 1.56) or abdominal obesity (OR = 1.08, 95% CI = 0.66, 1.76). Modeled isocaloric substitution of carbohydrates for plant, dairy, egg or fish protein was associated with lower likelihood of T2D (ranging from OR = 0.89, 95% CI = 0.83, 0.95-for dairy to OR = 0.91, 95% CI = 0.82, 0.99-egg) and prediabetes (ranging from OR = 0.82, 95% CI = 0.72, 0.92-for dairy to OR = 0.94, 95% CI = 0.89, 0.99-for fish). Public health strategies that reduce overall carbohydrates and saturated fat while increasing intake of plant and dairy proteins could mitigate the risk of metabolic diseases in India.

Indexed as

Cardiometabolic Risk FactorsDietAdultCross-Sectional StudiesDiabetes Mellitus, Type 2Dietary CarbohydratesDietary FatsDietary ProteinsDiet SurveysFemaleHumansIndiaMaleMiddle AgedNutrientsObesityDietary CarbohydratesDietary FatsDietary Proteins

Identifiers

PMID41028544
PMCPMC12618255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.