SynthesisNeurosurgical review2025
Traumatic brain injury among American indians/alaska natives in the united states: a comprehensive systematic review of the literature.
Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Post-Translational Modifications in Traumatic Brain Injury: Decoding the Proteomic Landscape and Molecular Mechanisms of Secondary Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Alzheimer's disease and related dementias and related health conditions among American Indian and Alaska Native Medicare beneficiaries.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic brain injury (TBI) represents a significant public health burden, particularly among American Indian and Alaska Native (AI/AN) populations in the United States, and particularly in the State of Alaska. This systematic review aims to evaluate the incidence, risk factors, outcomes, and healthcare disparities associated with TBI in this population and to identify strategies for prevention and improved management. Following PRISMA guidelines, we conducted a systematic review of Medline/PubMed, Google Scholar, Web of Science, Scopus, and Embase through May 2025. Inclusion criteria targeted studies involving AI/AN populations in the United States that reported on epidemiology, causes of injury, hospitalization, and mortality rates, as well as healthcare access. Data were extracted and synthesized qualitatively as we summarized, compared, and interpreted findings narratively based on common patterns and themes. The NIH Quality Assessment Tool was used to evaluate the quality of the included studies. Fourteen studies met the inclusion criteria. AI/ANs exhibited significantly higher TBI-related emergency visits (1,026 per 100,000), hospitalizations (186.7 per 100,000), and mortality rates (up to 65.9 per 100,000) compared to other racial groups. Leading causes included motor vehicle accidents, falls, and self-harm. Geographic isolation, limited neurosurgical infrastructure, and mistrust towards non-Native healthcare providers exacerbated disparities. Interventions like telemedicine, community health training, and culturally sensitive healthcare were identified as potential solutions. AI/AN populations, particularly those residing in the state of Alaska, face significantly higher incidence and worse outcomes from TBI due to systemic healthcare barriers and regional challenges. These disparities necessitate a multifaceted, culturally informed approach that encompasses enhanced access to care, preventive strategies, and collaboration with tribal health organizations to mitigate the burden of TBI and improve long-term outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.