Evidence map›Paper›PMID 41028359›Full record

SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026

Impact of treatment of molar-incisor hypomineralisation on children's oral health-related quality of life: a systematic review.

R P P Hoogeveen, E Momayez, C C Bonifacio, D J Manton, D Hesse

Abstract readSystematic Review
In one paragraph

Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Oral microbiome signatures of molar-incisor hypomineralisation: insights from a pilot study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  2. Review
  3. Article
  4. Trends in the prevalence of molar incisor hypomineralisation between 2018 and 2023: a comparison of two cross-sectional studies in elementary schools in Mexico.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R P P HoogeveenAcademic Center for Dentistry Amsterdam, Amsterdam, Netherlands.
E MomayezAcademic Center for Dentistry Amsterdam, Amsterdam, Netherlands.
C C BonifacioAcademic Center for Dentistry Amsterdam, Amsterdam, Netherlands.
D J MantonUniversity Medical Center Groningen, Groningen, Netherlands.
D HesseAcademic Center for Dentistry Amsterdam, Amsterdam, Netherlands. d.hesse@acta.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present systematic review aimed to investigate the impact of dental treatment for molar-incisor hypomineralisation (MIH) on the oral health-related quality of life (OHRQoL) in children.

methodsA literature search was conducted in four databases (Medline/PubMed, Embase, Scopus, and Google Scholar). Two independent reviewers selected studies amongst children with MIH who had received dental treatment, with OHRQoL assessed both before and after interventions. Data were critically summarised following the Synthesis Without Meta-analysis guideline. The risk of bias was assessed using the Cochrane ROB-2 tool, and the certainty of evidence was assessed using the GRADE approach.

resultsFrom the initial 460 identified studies, five were included. These studies included a total of 491 children aged 3-16 years (258 females and 233 males), each with at least one MIH-affected tooth. Qualitative synthesis indicated an improvement in OHRQoL in children following MIH treatment. However, the included studies exhibited potential biases in specific domains, and the certainty of evidence was rated as low.

conclusionTreatment of MIH-affected teeth positively impacts the OHRQoL of children.

Indexed as

Dental Enamel HypoplasiaOral HealthQuality of LifeAdolescentChildChild, PreschoolHumansChildrenDental treatmentMolar-incisor hypomineralisationOral health-related quality of lifeSystematic review

Identifiers

PMID41028359
PMCPMC13083423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.