Culture and Electrophysiological Analysis of Patient-Specific iPSCs Using Microelectrode Array Dishes.

Bayardo I Garay, Rita C R Perlingeiro

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bayardo I GarayDepartment of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, USA.

Rita C R PerlingeiroDepartment of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, USA. perli032@umn.edu.

Funding

Understanding the Transcriptional Networks and Physiologic Adaptations Governing the Clinical Manifestations of Duchenne Muscular DystrophyF30HL151138 · NHLBI · UNIVERSITY OF MINNESOTA · PI GARAY, BAYARDO ISIDORE · 2020 to 2023

$202k

NHLBI NIH HHS F30 HL151138

6 · The paper itself

Abstract

Microelectrode arrays offer an exciting opportunity to probe and characterize the functional status of dystrophin-deficient muscle tissue vis-à-vis patient-specific iPSC-derived skeletal muscle (SkM) and cardiac muscle (CM). Here, we present a method to culture and analyze baseline electrophysiological profiles of Duchenne muscular dystrophy (DMD) iPSC-SkM and iPSC-CM using MEA dishes.

Indexed as

Cell Culture TechniquesInduced Pluripotent Stem CellsMuscular Dystrophy, DuchenneCells, CulturedElectrophysiological PhenomenaHumansMicroelectrodesMuscle, SkeletalCardiac muscleConduction velocityDuchenne muscular dystrophyDystrophinElectrophysiologyField potentialsMicroelectrode arrayPatient-specific iPSCSkeletal muscle

Identifiers

PMID41028317

DOI10.1016/j.cardiores.2007.04.009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.